GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
ABC2_membrane_6 - ABC-2 family transporter protein
Pfam: PF06182 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0181
Length: 229
Sequences: 7092
Seq/Len: 30.97
HH_delta: 0.939 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
119_S185_V0.835153.627
129_S214_S0.616412.677
170_Q174_T0.614832.670
129_S207_I0.599862.605
125_L207_I0.546272.373
133_I217_L0.530152.303
167_G171_F0.522052.267
201_L205_I0.518812.253
72_N75_F0.506362.199
212_L216_L0.480342.086
168_W171_F0.479062.081
126_I210_L0.473192.055
197_L201_L0.467852.032
171_F175_F0.452471.965
184_Y199_I0.443141.925
168_W172_I0.44251.922
123_G182_I0.440361.913
181_Y202_I0.431941.876
167_G170_Q0.422221.834
171_F174_T0.415751.806
36_F187_A0.402721.749
129_S210_L0.401071.742
166_P170_Q0.39311.707
57_D80_R0.378431.644
173_L180_A0.377581.640
133_I213_L0.377041.638
181_Y199_I0.366521.592
94_I117_I0.353571.536
198_F202_I0.350471.522
126_I207_I0.349641.519
184_Y188_R0.34871.515
119_S189_I0.340821.480
198_F201_L0.340061.477
162_L174_T0.338991.472
129_S211_F0.332931.446
74_L215_R0.332231.443
122_L204_A0.330331.435
202_I205_I0.329681.432
115_L118_L0.327971.424
200_L204_A0.319711.389
165_F173_L0.31971.389
209_V213_L0.313891.363
122_L207_I0.312391.357
136_L217_L0.311341.352
204_A208_L0.308231.339
114_L118_L0.303071.316
115_L189_I0.301961.311
215_R219_R0.295631.284
202_I206_W0.294651.280
157_G160_Y0.294461.279
216_L220_K0.293911.277
140_W143_E0.29311.273
119_S200_L0.29091.263
123_G127_N0.289471.257
43_Y179_F0.288271.252
125_L211_F0.27981.215
183_S187_A0.279771.215
36_F40_F0.278871.211
113_I117_I0.278731.211
209_V212_L0.278581.210
118_L122_L0.278041.208
94_I98_I0.277371.205
55_S59_R0.276991.203
174_T180_A0.275961.199
45_I49_G0.275711.197
117_I121_L0.275691.197
72_N215_R0.274811.194
162_L173_L0.27461.193
109_S112_N0.272481.183
174_T181_Y0.272241.182
146_G149_Y0.270531.175
90_L121_L0.270161.173
177_L180_A0.266931.159
162_L170_Q0.261571.136
111_L115_L0.260421.131
123_G186_P0.260241.130
118_L200_L0.259331.126
34_G100_A0.254921.107
201_L204_A0.251331.092
188_R193_K0.249211.082
40_F153_S0.248551.080
133_I214_S0.247751.076
207_I211_F0.247181.074
79_F83_G0.247011.073
206_W210_L0.246651.071
158_A183_S0.243891.059
205_I209_V0.243861.059
65_Q68_L0.242371.053
112_N115_L0.241061.047
124_F128_F0.240411.044
199_I203_Q0.239721.041
69_R74_L0.239251.039
132_F136_L0.237061.030
134_I144_S0.237031.029
57_D62_E0.234121.017
204_A207_I0.233711.015
211_F215_R0.233561.014
152_Y177_L0.232631.010
35_F40_F0.228270.991
39_I182_I0.227920.990
126_I129_S0.227010.986
93_G120_L0.22680.985
165_F169_I0.226750.985
181_Y206_W0.226390.983
40_F158_A0.226370.983
35_F39_I0.221910.964
188_R192_G0.220780.959
29_M33_Y0.220520.958
126_I206_W0.220310.957
138_A147_L0.219530.953
212_L215_R0.219070.951
205_I208_L0.218490.949
181_Y185_V0.218080.947
157_G162_L0.217510.945
55_S58_I0.217230.943
166_P169_I0.216020.938
122_L203_Q0.21420.930
138_A145_W0.211290.918
35_F38_L0.210780.915
157_G180_A0.208870.907
69_R76_Y0.208590.906
127_N131_F0.207120.900
210_L214_S0.2070.899
37_F40_F0.20650.897
66_Y69_R0.205840.894
161_P164_I0.203810.885
131_F135_G0.203540.884
132_F135_G0.20240.879
39_I186_P0.202330.879
213_L216_L0.202170.878
95_I99_Y0.202030.877
157_G166_P0.199950.868
50_N131_F0.199650.867
114_L117_I0.199540.867
185_V188_R0.199470.866
124_F127_N0.198640.863
51_I56_E0.198390.862
67_L222_L0.19610.852
126_I203_Q0.195920.851
29_M187_A0.194050.843
155_L173_L0.193950.842
133_I137_L0.193230.839
185_V199_I0.192250.835
43_Y127_N0.191190.830
187_A191_L0.191110.830
216_L219_R0.190520.827
39_I179_F0.190490.827
36_F158_A0.189850.825
185_V203_Q0.189590.823
138_A144_S0.189490.823
46_F127_N0.189470.823
218_W222_L0.189250.822
65_Q69_R0.188690.820
196_P199_I0.188440.818
162_L180_A0.187750.815
51_I54_I0.187170.813
111_L114_L0.186390.810
135_G144_S0.185890.807
139_F142_T0.184920.803
89_F93_G0.182530.793
42_L46_F0.182210.791
80_R84_P0.182210.791
138_A143_E0.182160.791
53_E57_D0.18210.791
42_L45_I0.180870.786
116_F120_L0.180570.784
111_L189_I0.180140.782
32_Y35_F0.17810.774
128_F142_T0.177740.772
139_F143_E0.177470.771
155_L177_L0.17710.769
50_N53_E0.176720.768
112_N189_I0.176270.766
141_F148_S0.176140.765
116_F189_I0.17590.764
86_S125_L0.175650.763
122_L185_V0.175210.761
41_G45_I0.175210.761
182_I203_Q0.174140.756
62_E66_Y0.174110.756
74_L78_L0.174050.756
163_S166_P0.173340.753
157_G165_F0.173120.752
98_I103_Q0.172850.751
115_L119_S0.172760.750
75_F78_L0.172680.750
36_F39_I0.172470.749
59_R141_F0.171810.746
39_I183_S0.171470.745
96_L100_A0.171050.743
76_Y84_P0.171030.743
109_S114_L0.17040.740
204_A216_L0.170340.740
62_E65_Q0.169940.738
162_L184_Y0.169680.737
66_Y71_V0.169220.735
157_G184_Y0.169150.735
129_S133_I0.169110.734
74_L211_F0.1690.734
140_W221_G0.168970.734
122_L200_L0.167750.729
77_L132_F0.166970.725
157_G177_L0.166280.722
157_G173_L0.165920.721
136_L221_G0.165530.719
129_S136_L0.164870.716
39_I116_F0.164840.716
70_P161_P0.164590.715
208_L212_L0.164220.713
64_D68_L0.164110.713
219_R222_L0.16370.711
111_L116_F0.163590.711
121_L125_L0.163480.710
40_F44_M0.162620.706
123_G189_I0.162560.706
120_L182_I0.161230.700
57_D73_Y0.160950.699
115_L212_L0.160080.695
207_I218_W0.159320.692
134_I147_L0.159280.692
217_L220_K0.159190.691
163_S170_Q0.159060.691
40_F179_F0.158990.691
217_L221_G0.158720.689
42_L123_G0.158380.688
36_F43_Y0.158110.687
159_I186_P0.15810.687
118_L204_A0.155640.676
37_F41_G0.15550.675
162_L181_Y0.15540.675
56_E60_T0.155350.675
98_I101_L0.154410.671
185_V200_L0.154340.670
193_K198_F0.154290.670
142_T218_W0.154190.670
185_V189_I0.154110.669
75_F79_F0.153630.667
175_F180_A0.153440.666
57_D66_Y0.152750.663
163_S168_W0.15210.661
64_D67_L0.15210.661
199_I202_I0.151730.659
61_G64_D0.151010.656
35_F186_P0.150870.655
130_I210_L0.150740.655
40_F49_G0.150620.654
71_V75_F0.150470.654
39_I123_G0.150370.653
60_T145_W0.150240.653
47_F159_I0.150150.652
153_S159_I0.149820.651
156_S179_F0.14970.650
58_I153_S0.149180.648
76_Y218_W0.147930.643
208_L211_F0.147840.642
181_Y203_Q0.147720.642
34_G41_G0.147640.641
44_M153_S0.147390.640
184_Y187_A0.147160.639
158_A187_A0.146620.637
156_S183_S0.146480.636
197_L202_I0.146240.635
68_L71_V0.146190.635
32_Y36_F0.146090.635
213_L217_L0.145770.633
37_F45_I0.145730.633
203_Q206_W0.145190.631
169_I173_L0.144410.627
207_I210_L0.144360.627
44_M152_Y0.144350.627
42_L128_F0.144170.626
38_L96_L0.143730.624
136_L218_W0.142610.619
92_V182_I0.142530.619
161_P165_F0.141680.615
47_F148_S0.141560.615
81_N164_I0.141510.615
179_F183_S0.141210.613
159_I179_F0.141160.613
205_I212_L0.14110.613
182_I185_V0.141040.613
203_Q207_I0.140620.611
57_D79_F0.140320.609
125_L129_S0.14030.609
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2wswA0.73364.40.939
1iflA0.22713.80.941
3zuxA0.31443.40.942
1fdmA0.21832.60.946
3pjzA0.29692.10.948
2lx0A0.13971.90.949
1ifkA0.22271.70.95
2m20A0.16161.40.952
2yevB0.31881.30.953
3j08A0.23581.30.954
If you are interested in a protein containing this domain,
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