GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
PDR_CDR - CDR ABC transporter
Pfam: PF06422 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0181
Length: 103
Sequences: 739
Seq/Len: 7.17
HH_delta: 0.932 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
52_F56_I0.571613.422
25_Q35_D0.47672.853
32_S35_D0.464132.778
38_E44_S0.441382.642
88_G91_P0.36962.212
45_Y48_R0.349352.091
64_V68_L0.324571.943
36_Y41_Y0.321081.922
25_Q28_S0.319911.915
18_V26_P0.303581.817
22_V40_S0.299691.794
34_D45_Y0.272371.630
61_F65_L0.261221.564
86_K89_K0.259711.555
35_D39_E0.258881.550
21_V24_A0.257231.540
20_A24_A0.245081.467
57_A60_I0.234641.404
75_F79_G0.231231.384
48_R52_F0.230541.380
2_L17_Q0.224421.343
50_R54_I0.220041.317
35_D38_E0.218381.307
1_Q91_P0.211541.266
22_V39_E0.208241.246
54_I61_F0.208121.246
56_I60_I0.20631.235
49_W53_G0.201471.206
83_L86_K0.20041.200
73_I76_E0.198241.187
57_A62_F0.1951.167
80_G83_L0.194221.163
66_T81_E0.186661.117
57_A61_F0.183821.100
78_S81_E0.181861.089
47_H50_R0.180031.078
59_W69_A0.17221.031
28_S35_D0.172111.030
17_Q59_W0.169041.012
69_A83_L0.166980.999
5_S9_Y0.165940.993
59_W63_I0.162770.974
17_Q21_V0.162370.972
34_D83_L0.160560.961
2_L42_G0.15910.952
65_L70_T0.156020.934
55_L58_F0.155990.934
66_T79_G0.153950.922
79_G82_V0.153910.921
24_A28_S0.152810.915
60_I64_V0.152440.912
44_S47_H0.149630.896
68_L72_F0.148530.889
41_Y85_F0.147170.881
10_D17_Q0.146660.878
29_T32_S0.143240.857
1_Q92_K0.143050.856
30_Y64_V0.142950.856
25_Q46_S0.141940.850
66_T73_I0.140310.840
78_S83_L0.140070.838
5_S11_N0.139920.838
63_I73_I0.138970.832
63_I86_K0.138910.831
43_Y50_R0.137460.823
10_D16_N0.136830.819
54_I60_I0.136380.816
62_F82_V0.136160.815
50_R53_G0.134780.807
2_L29_T0.134740.807
39_E74_K0.133380.798
3_I45_Y0.133060.796
46_S85_F0.132630.794
43_Y66_T0.131660.788
7_P20_A0.130790.783
59_W77_K0.130180.779
78_S82_V0.129760.777
12_I17_Q0.129710.776
51_N55_L0.128620.770
75_F78_S0.128490.769
34_D66_T0.127810.765
70_T73_I0.125710.752
39_E46_S0.125440.751
16_N90_A0.125150.749
82_V85_F0.124710.746
30_Y34_D0.124460.745
7_P10_D0.124370.744
50_R83_L0.124290.744
67_L77_K0.123950.742
63_I67_L0.123740.741
69_A74_K0.122760.735
37_L44_S0.122710.735
67_L74_K0.122440.733
18_V24_A0.12230.732
80_G87_R0.1220.730
20_A47_H0.12190.730
85_F88_G0.121840.729
56_I71_E0.121830.729
24_A91_P0.121190.725
38_E42_G0.120910.724
69_A75_F0.12020.719
2_L79_G0.119730.717
70_T74_K0.119150.713
60_I72_F0.118750.711
62_F66_T0.118740.711
39_E68_L0.117360.702
51_N54_I0.116490.697
83_L89_K0.116450.697
64_V72_F0.115910.694
49_W52_F0.115870.694
2_L48_R0.114830.687
66_T74_K0.114420.685
1_Q29_T0.113640.680
82_V86_K0.113350.678
80_G84_V0.111970.670
31_V40_S0.111450.667
38_E60_I0.111450.667
25_Q31_V0.111420.667
22_V55_L0.111320.666
37_L67_L0.111010.664
44_S48_R0.110810.663
44_S85_F0.110070.659
51_N70_T0.109070.653
2_L82_V0.109020.653
41_Y64_V0.107190.642
47_H51_N0.106830.639
28_S65_L0.106730.639
47_H53_G0.106550.638
55_L73_I0.106440.637
65_L69_A0.106270.636
56_I59_W0.1060.634
2_L63_I0.105660.632
4_P17_Q0.104750.627
58_F62_F0.10470.627
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2jo1A0.553413.30.932
2kncA0.524311.30.934
1qb3A0.873811.30.934
3qy2A0.8641100.935
1rzhH0.61179.90.936
1pucA0.78649.70.936
3um7A0.79619.40.936
3q3uA0.31078.60.937
3ukmA0.621480.938
2xl1A0.25247.90.938
If you are interested in a protein containing this domain,
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