GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
GWT1 - GWT1
Pfam: PF06423 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 136
Sequences: 717
Seq/Len: 5.27
HH_delta: 0.918 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
22_L87_T0.274992.388
59_Y81_W0.273172.372
67_E76_L0.239122.077
125_F129_N0.22111.920
62_L67_E0.212611.846
95_L100_L0.204381.775
18_I83_L0.197771.718
15_I83_L0.194741.691
62_L76_L0.194381.688
18_I79_V0.188771.639
56_W88_F0.183831.597
115_D122_L0.169871.475
49_L53_F0.155081.347
118_N125_F0.152341.323
12_Y70_S0.152041.320
15_I122_L0.150991.311
94_L98_L0.150691.309
5_G78_Y0.148981.294
2_N12_Y0.147221.279
8_S78_Y0.144511.255
121_G126_L0.143461.246
112_C116_A0.142581.238
8_S128_A0.137661.196
8_S12_Y0.135671.178
71_R75_N0.135011.173
78_Y125_F0.133621.160
52_S88_F0.133491.159
15_I74_A0.132451.150
54_I58_L0.131671.144
25_Y87_T0.131371.141
50_I55_F0.130811.136
86_N126_L0.129881.128
49_L61_L0.128031.112
70_S73_L0.127361.106
30_S47_K0.126221.096
21_S85_F0.126121.095
3_R12_Y0.125291.088
53_F57_A0.124841.084
4_E12_Y0.124751.083
117_I124_V0.12421.079
72_R129_N0.122811.067
67_E77_P0.12281.066
45_L58_L0.122551.064
87_T91_A0.122361.063
19_G83_L0.122051.060
70_S74_A0.121321.054
83_L93_Y0.120021.042
71_R118_N0.119811.041
55_F95_L0.119751.040
65_Y122_L0.119681.039
52_S84_A0.119471.038
114_L120_N0.119121.035
96_I110_T0.118651.030
120_N123_F0.118571.030
3_R70_S0.11751.020
103_P111_P0.117231.018
2_N129_N0.117031.016
2_N71_R0.116051.008
102_R124_V0.115691.005
12_Y74_A0.115261.001
43_K61_L0.11521.000
46_I53_F0.114670.996
93_Y121_G0.113780.988
6_I9_L0.113070.982
31_S43_K0.113010.981
28_P78_Y0.112730.979
54_I57_A0.112570.978
58_L61_L0.11230.975
32_S44_L0.111740.970
70_S82_V0.111590.969
16_Y20_V0.110660.961
84_A88_F0.110410.959
8_S127_L0.109490.951
46_I50_I0.109450.951
58_L64_S0.109150.948
82_V86_N0.108330.941
2_N70_S0.107990.938
75_N81_W0.107510.934
22_L48_L0.10740.933
6_I76_L0.107230.931
102_R110_T0.107150.931
16_Y125_F0.106480.925
3_R9_L0.106350.924
24_R50_I0.105110.913
20_V121_G0.104870.911
57_A60_Y0.104870.911
31_S45_L0.104150.905
4_E78_Y0.103610.900
118_N121_G0.103010.895
56_W84_A0.102960.894
56_W85_F0.102720.892
5_G70_S0.102650.891
23_G97_E0.102170.887
8_S74_A0.102150.887
11_G90_L0.102030.886
43_K47_K0.102010.886
2_N118_N0.101980.886
78_Y86_N0.101660.883
31_S53_F0.101640.883
8_S13_L0.100760.875
123_F130_L0.100640.874
20_V87_T0.100530.873
78_Y115_D0.100490.873
19_G86_N0.100390.872
92_L104_K0.099690.866
76_L128_A0.09960.865
61_L65_Y0.099410.863
49_L88_F0.099270.862
3_R71_R0.099140.861
18_I119_R0.098810.858
11_G118_N0.098670.857
16_Y72_R0.098510.856
98_L118_N0.098430.855
111_P116_A0.098230.853
14_A18_I0.098160.852
2_N72_R0.097910.850
72_R126_L0.097780.849
11_G48_L0.097170.844
43_K50_I0.097170.844
80_L127_L0.096690.840
29_P32_S0.09660.839
71_R125_F0.096490.838
93_Y117_I0.096240.836
71_R74_A0.096080.834
25_Y29_P0.095730.831
29_P104_K0.095570.830
55_F80_L0.095120.826
12_Y15_I0.094890.824
4_E124_V0.094550.821
3_R118_N0.094530.821
2_N5_G0.094290.819
78_Y114_L0.093890.815
70_S129_N0.093740.814
46_I49_L0.093470.812
18_I55_F0.093460.812
32_S99_L0.093140.809
32_S54_I0.092920.807
2_N75_N0.092630.804
13_L70_S0.092630.804
11_G116_A0.092270.801
59_Y121_G0.092230.801
13_L20_V0.092130.800
28_P92_L0.092060.800
75_N128_A0.091990.799
68_P77_P0.091920.798
9_L19_G0.091910.798
59_Y84_A0.091880.798
2_N74_A0.091770.797
16_Y71_R0.091720.797
17_L84_A0.091550.795
59_Y118_N0.091550.795
19_G59_Y0.091530.795
23_G90_L0.091520.795
18_I66_I0.091480.794
75_N129_N0.091190.792
91_A100_L0.091080.791
32_S57_A0.091070.791
4_E70_S0.090930.790
33_S46_I0.090810.789
83_L121_G0.090730.788
5_G12_Y0.090670.787
18_I21_S0.090610.787
70_S75_N0.090540.786
9_L70_S0.090510.786
76_L80_L0.090420.785
28_P101_F0.090050.782
51_L104_K0.089880.781
16_Y81_W0.089850.780
27_L123_F0.089640.778
28_P48_L0.089620.778
99_L130_L0.089330.776
85_F126_L0.088920.772
92_L96_I0.088690.770
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4ezcA0.904420.20.918
4j05A0.852910.90.926
3mp7A0.88248.10.93
3k3fA0.88245.90.934
4apsA0.88975.20.936
1rh5A0.84564.60.937
1pw4A0.83094.40.938
2gfpA0.82354.30.938
3o7qA0.83093.80.94
1pveA0.176530.942
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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