GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF1211 - Protein of unknown function (DUF1211)
Pfam: PF06736 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 92
Sequences: 469
Seq/Len: 5.1
HH_delta: 0.928 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
57_A82_L0.505513.678
14_A17_L0.297832.167
6_F15_M0.241591.758
49_Y89_S0.23281.694
1_E4_E0.221371.611
74_D77_I0.21881.592
7_S63_H0.218051.587
63_H81_N0.21611.572
6_F9_A0.199161.449
13_I20_L0.19891.447
19_V90_L0.195471.422
6_F10_V0.194711.417
9_A12_A0.191471.393
61_Y75_R0.188211.370
4_E64_H0.187841.367
22_L42_L0.187791.366
40_W43_W0.187271.363
17_L89_S0.185531.350
11_F84_F0.18321.333
14_A56_I0.181161.318
21_E25_P0.175141.274
9_A13_I0.174261.268
40_W50_L0.172781.257
7_S11_F0.170161.238
83_L87_F0.166731.213
43_W47_L0.165171.202
49_Y86_F0.163481.190
9_A85_L0.162791.185
2_R8_D0.162581.183
15_M56_I0.162291.181
50_L86_F0.159111.158
73_V77_I0.158711.155
7_S56_I0.157541.146
4_E81_N0.153121.114
8_D20_L0.15261.110
55_I59_F0.15231.108
5_A9_A0.148731.082
7_S81_N0.146431.066
43_W46_L0.144851.054
11_F88_I0.138671.009
58_M62_S0.137140.998
5_A20_L0.136450.993
15_M18_L0.135250.984
18_L49_Y0.134340.978
84_F88_I0.133670.973
10_V57_A0.132930.967
26_S41_A0.13230.963
36_W51_L0.129070.939
51_L82_L0.127520.928
18_L56_I0.126580.921
14_A88_I0.126550.921
8_D60_W0.126370.920
1_E69_H0.12510.910
66_I72_K0.124540.906
61_Y78_I0.124340.905
53_F84_F0.122270.890
36_W40_W0.122190.889
44_P91_I0.122110.889
67_F70_I0.12180.886
14_A89_S0.121490.884
19_V89_S0.121260.882
48_A67_F0.120850.879
40_W91_I0.120810.879
57_A66_I0.120210.875
69_H80_L0.119930.873
9_A21_E0.119370.869
14_A51_L0.118570.863
42_L45_Q0.118360.861
26_S45_Q0.117750.857
10_V15_M0.117550.855
15_M79_W0.117270.853
6_F48_A0.116610.849
37_E40_W0.116250.846
59_F84_F0.115730.842
1_E9_A0.115720.842
41_A45_Q0.115670.842
67_F77_I0.115380.840
2_R63_H0.115040.837
25_P49_Y0.113980.829
48_A52_S0.113760.828
61_Y82_L0.113720.827
61_Y79_W0.113630.827
3_L82_L0.11340.825
84_F89_S0.113380.825
33_E40_W0.113330.825
39_L46_L0.113030.822
5_A73_V0.112970.822
62_S81_N0.111780.813
12_A17_L0.11140.811
47_L54_F0.111250.810
55_I90_L0.111120.809
35_L70_I0.110950.807
18_L48_A0.110770.806
35_L44_P0.110170.802
10_V36_W0.110060.801
41_A69_H0.109930.800
2_R18_L0.109520.797
1_E5_A0.109510.797
65_R75_R0.10940.796
6_F56_I0.108770.791
57_A78_I0.108640.791
19_V85_L0.108510.790
25_P62_S0.108210.787
39_L68_R0.10730.781
19_V74_D0.10720.780
9_A16_T0.106430.774
3_L41_A0.106360.774
75_R87_F0.105380.767
86_F90_L0.105370.767
5_A12_A0.104850.763
59_F75_R0.104650.761
38_A41_A0.104610.761
22_L53_F0.104420.760
5_A8_D0.101930.742
54_F59_F0.101220.737
3_L66_I0.100990.735
34_S70_I0.100940.734
6_F62_S0.099780.726
23_Q26_S0.099750.726
11_F42_L0.099010.720
3_L77_I0.098980.720
2_R5_A0.098970.720
47_L51_L0.098530.717
19_V87_F0.098120.714
71_K76_R0.097760.711
13_I16_T0.097740.711
6_F64_H0.097550.710
10_V34_S0.097430.709
8_D49_Y0.097080.706
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3m73A0.60873.70.928
3fnrA0.39132.50.934
4bg2A0.3372.40.934
3t5vB12.40.934
1rdsA0.3372.20.936
2wvfA0.3372.10.936
2hbjA0.4131.90.938
3efdK0.10871.90.938
2bj7A0.32611.80.938
3kaeA0.68481.50.941
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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