GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
HET - Heterokaryon incompatibility protein (HET)
Pfam: PF06985 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 139
Sequences: 2088
Seq/Len: 15.02
HH_delta: 0.928 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
53_N56_D0.877144.398
60_K64_I0.724463.632
3_A74_A0.610313.060
3_A77_V0.508532.550
2_V43_R0.486792.441
33_A45_L0.475832.386
2_V76_L0.470892.361
53_N59_E0.460862.311
63_Q66_L0.449232.252
7_V129_P0.442982.221
74_A77_V0.438232.197
79_V130_W0.419482.103
6_Y49_A0.416542.088
2_V42_I0.413032.071
130_W136_T0.411842.065
4_L33_A0.410672.059
67_M71_Y0.406662.039
31_Q35_R0.365911.835
30_L47_I0.345081.730
1_Y73_N0.337261.691
57_D60_K0.326771.638
28_E32_D0.324321.626
57_D61_S0.314571.577
14_K17_I0.304141.525
40_L78_I0.297591.492
6_Y30_L0.275951.383
30_L33_A0.274921.378
66_L69_D0.270581.357
24_L50_L0.257671.292
38_R43_R0.257631.292
63_Q70_I0.256681.287
82_G128_R0.254881.278
85_D88_S0.252051.264
4_L47_I0.247681.242
83_S88_S0.24611.234
133_R139_E0.244731.227
67_M133_R0.244051.224
2_V37_A0.239311.200
2_V78_I0.232641.166
36_I78_I0.229871.152
3_A70_I0.226881.137
69_D73_N0.220351.105
88_S128_R0.218031.093
54_Q60_K0.217331.090
34_L37_A0.217151.089
39_A43_R0.215051.078
42_I75_S0.213961.073
45_L78_I0.212441.065
36_I83_S0.210881.057
4_L80_W0.208081.043
128_R131_F0.20791.042
60_K65_A0.207711.041
36_I40_L0.205011.028
89_D93_R0.204041.023
7_V130_W0.203231.019
7_V60_K0.201691.011
135_W139_E0.20151.010
27_P34_L0.200621.006
15_Q31_Q0.197770.992
91_A95_L0.195690.981
30_L80_W0.192790.967
66_L70_I0.192590.966
56_D59_E0.191360.959
16_P25_S0.191130.958
96_R103_P0.190630.956
26_L29_N0.189870.952
131_F137_L0.189150.948
125_L128_R0.188840.947
81_L131_F0.187420.940
54_Q70_I0.187320.939
8_W67_M0.186430.935
13_D16_P0.185840.932
20_D24_L0.185710.931
14_K19_V0.183110.918
121_S125_L0.182450.915
84_D128_R0.180550.905
29_N34_L0.179760.901
90_L93_R0.179490.900
8_W54_Q0.178330.894
96_R101_P0.176650.886
37_A78_I0.174750.876
35_R39_A0.173470.870
68_G72_S0.172980.867
49_A134_G0.172710.866
60_K63_Q0.171770.861
71_Y138_Q0.171290.859
98_L102_S0.170340.854
26_L131_F0.169530.850
59_E63_Q0.169360.849
58_E61_S0.16910.848
84_D89_D0.1680.842
85_D124_D0.167530.840
61_S65_A0.167370.839
48_D51_C0.166090.833
13_D28_E0.165770.831
89_D96_R0.164420.824
17_I20_D0.164030.822
29_N80_W0.162660.816
91_A94_S0.162510.815
6_Y47_I0.161490.810
18_P21_G0.160830.806
52_I63_Q0.160630.805
33_A36_I0.159650.800
8_W133_R0.157470.789
101_P104_Q0.157060.787
19_V24_L0.155350.779
93_R103_P0.155170.778
37_A42_I0.154850.776
32_D35_R0.154310.774
89_D94_S0.15430.774
47_I77_V0.15410.773
54_Q63_Q0.153740.771
92_F97_S0.153680.770
101_P105_E0.153520.770
15_Q21_G0.153230.768
51_C54_Q0.153090.768
17_I24_L0.152590.765
69_D72_S0.152010.762
69_D78_I0.150260.753
33_A37_A0.149990.752
14_K18_P0.149220.748
37_A43_R0.148460.744
134_G137_L0.148250.743
48_D52_I0.147880.741
26_L36_I0.147710.741
101_P113_A0.147030.737
93_R96_R0.146550.735
44_Y138_Q0.145690.730
91_A96_R0.143360.719
92_F99_S0.143250.718
71_Y133_R0.142530.715
64_I130_W0.141480.709
34_L45_L0.141410.709
50_L54_Q0.141110.707
30_L34_L0.13970.700
10_D13_D0.139640.700
4_L30_L0.138580.695
53_N81_L0.138580.695
58_E72_S0.138480.694
100_S113_A0.138120.692
100_S105_E0.137470.689
44_Y51_C0.137440.689
27_P30_L0.137060.687
100_S104_Q0.136840.686
70_I77_V0.136530.685
8_W49_A0.136270.683
59_E64_I0.136210.683
102_S105_E0.135980.682
127_S132_T0.1350.677
26_L31_Q0.134860.676
99_S103_P0.134070.672
62_R65_A0.133890.671
6_Y130_W0.133550.670
1_Y5_S0.133340.669
33_A38_R0.133170.668
104_Q132_T0.133030.667
80_W83_S0.132970.667
28_E31_Q0.132920.666
100_S103_P0.131810.661
9_G45_L0.131550.660
129_P132_T0.131050.657
56_D62_R0.130660.655
6_Y136_T0.13060.655
17_I21_G0.129930.651
97_S102_S0.12980.651
99_S105_E0.12970.650
32_D36_I0.129080.647
5_S8_W0.129040.647
29_N33_A0.128460.644
53_N131_F0.12710.637
120_S123_R0.126990.637
82_G129_P0.126370.634
67_M138_Q0.126360.634
90_L96_R0.125880.631
13_D17_I0.125310.628
52_I64_I0.125160.627
14_K25_S0.125150.627
58_E62_R0.125010.627
94_S97_S0.124920.626
98_L101_P0.124660.625
49_A130_W0.124080.622
6_Y29_N0.123650.620
48_D54_Q0.122770.616
76_L79_V0.122740.615
56_D67_M0.12270.615
72_S119_W0.122380.614
26_L33_A0.122250.613
97_S105_E0.122020.612
128_R136_T0.1220.612
89_D92_F0.12130.608
42_I76_L0.121220.608
15_Q18_P0.121060.607
45_L85_D0.120910.606
80_W131_F0.120820.606
29_N37_A0.120490.604
94_S98_L0.120360.603
69_D121_S0.12030.603
2_V77_V0.120110.602
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2pmrA0.208614.50.928
1mswD0.884910.30.933
3spaA0.87057.20.937
3zq7A0.33097.20.937
2vpvA0.35256.30.939
2v7kA0.85616.20.939
2e1mB0.40295.30.941
3uitA0.39574.30.943
3dnfA0.84894.10.944
2qtxA0.37413.90.944
If you are interested in a protein containing this domain,
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