GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
TctB - Tripartite tricarboxylate transporter TctB family
Pfam: PF07331 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 141
Sequences: 1287
Seq/Len: 9.13
HH_delta: 0.903 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
85_Y98_T0.602134.020
14_G46_L0.450383.007
11_L46_L0.380762.542
14_G42_G0.375142.505
7_G49_S0.352262.352
18_L42_G0.334492.233
7_G53_L0.320212.138
107_L114_W0.315792.108
92_L100_L0.303272.025
11_L49_S0.288791.928
123_V127_V0.2851.903
18_L39_R0.274851.835
99_F125_A0.271051.810
119_L123_V0.264841.768
18_L46_L0.257151.717
12_A16_V0.249961.669
35_G39_R0.248441.659
15_A19_Y0.246831.648
43_I47_I0.244111.630
111_E117_L0.243021.623
32_P36_F0.235161.570
103_F121_S0.233851.561
78_V105_F0.229061.529
21_A39_R0.222631.486
94_F98_T0.21291.421
14_G45_L0.211321.411
4_L56_S0.210421.405
14_G49_S0.206911.381
115_L119_L0.206411.378
130_F134_K0.205681.373
116_R120_I0.204531.366
77_L108_L0.203171.356
129_Y133_A0.19921.330
10_F49_S0.195751.307
17_F42_G0.192561.286
4_L57_F0.192091.283
81_L108_L0.190791.274
85_Y94_F0.187771.254
103_F118_L0.18611.243
113_R116_R0.182261.217
7_G56_S0.180481.205
3_D7_G0.180131.203
101_F105_F0.179471.198
127_V131_V0.179111.196
21_A35_G0.179021.195
99_F122_V0.177881.188
20_Q23_Q0.177681.186
98_T125_A0.177541.185
81_L105_F0.175331.171
102_L106_M0.174411.164
84_L88_L0.172391.151
121_S125_A0.172361.151
107_L117_L0.170761.140
24_I35_G0.170231.137
88_L91_Y0.170071.135
95_I129_Y0.169741.133
124_F128_I0.16821.123
42_G46_L0.166261.110
37_F41_L0.161941.081
3_D55_R0.159891.068
129_Y134_K0.157051.049
44_L48_L0.156361.044
80_G84_L0.155941.041
74_R108_L0.154211.030
3_D56_S0.154021.028
114_W117_L0.153551.025
22_F39_R0.150891.007
14_G17_F0.14940.997
16_V20_Q0.149380.997
19_Y22_F0.148460.991
21_A42_G0.147660.986
51_L55_R0.146470.978
33_G132_F0.146350.977
94_F128_I0.146290.977
78_V108_L0.144310.963
50_L54_V0.143520.958
102_L121_S0.142960.954
10_F45_L0.140880.941
101_F136_L0.140690.939
112_R116_R0.140480.938
99_F121_S0.140040.935
88_L92_L0.138260.923
13_F45_L0.138040.922
89_L140_L0.136940.914
72_W76_L0.13570.906
15_A122_V0.135160.902
81_L136_L0.13320.889
93_G136_L0.133150.889
112_R117_L0.132860.887
47_I51_L0.132570.885
16_V23_Q0.132220.883
34_P106_M0.131370.877
8_L22_F0.130220.869
16_V19_Y0.130080.868
109_L128_I0.128530.858
81_L101_F0.127130.849
45_L120_I0.126670.846
84_L104_A0.125990.841
12_A23_Q0.125890.841
100_L113_R0.125320.837
96_I99_F0.125080.835
18_L35_G0.124610.832
12_A19_Y0.124580.832
91_Y97_A0.124090.828
111_E116_R0.123350.824
132_F138_V0.123320.823
116_R119_L0.123070.822
83_V88_L0.122230.816
11_L53_L0.121930.814
23_Q119_L0.121060.808
39_R43_I0.120930.807
87_L90_E0.12050.805
94_F140_L0.120090.802
55_R58_R0.118490.791
34_P132_F0.117750.786
55_R59_G0.117440.784
4_L53_L0.117010.781
31_S98_T0.116830.780
14_G18_L0.116760.780
85_Y109_L0.115120.769
24_I139_P0.114720.766
55_R82_L0.114660.766
14_G53_L0.114190.762
98_T109_L0.114040.761
54_V58_R0.113770.760
45_L89_L0.113710.759
26_S39_R0.11330.756
65_E126_A0.113130.755
86_V133_A0.113120.755
47_I57_F0.112730.753
47_I50_L0.112490.751
8_L13_F0.11190.747
133_A136_L0.111450.744
89_L139_P0.110990.741
3_D85_Y0.110950.741
95_I126_A0.110570.738
103_F107_L0.110540.738
69_R73_K0.110390.737
134_K137_G0.108220.723
132_F139_P0.108210.722
23_Q41_L0.107990.721
35_G132_F0.107810.720
11_L50_L0.107720.719
109_L112_R0.107650.719
92_L97_A0.107510.718
95_I99_F0.107450.717
105_F108_L0.107290.716
94_F130_F0.106960.714
28_P138_V0.106860.713
26_S32_P0.106850.713
41_L137_G0.106540.711
36_F39_R0.106520.711
91_Y122_V0.106520.711
18_L43_I0.106320.710
3_D52_L0.105890.707
103_F117_L0.105830.707
43_I64_E0.105730.706
88_L97_A0.105160.702
74_R109_L0.105150.702
46_L50_L0.105080.702
54_V123_V0.10440.697
101_F104_A0.104040.695
118_L122_V0.103810.693
27_F36_F0.103490.691
85_Y101_F0.103170.689
43_I127_V0.103170.689
125_A132_F0.102660.685
52_L95_I0.102550.685
78_V98_T0.10240.684
119_L122_V0.102160.682
24_I102_L0.101970.681
94_F129_Y0.101890.680
31_S138_V0.101630.679
89_L98_T0.10150.678
26_S35_G0.100930.674
3_D102_L0.100890.674
106_M117_L0.10040.670
21_A36_F0.100040.668
34_P89_L0.100030.668
63_D96_I0.100030.668
131_V135_L0.099570.665
16_V118_L0.09950.664
17_F45_L0.099420.664
15_A46_L0.099330.663
77_L82_L0.098740.659
90_E133_A0.09860.658
39_R42_G0.098570.658
5_I73_K0.098490.658
40_L95_I0.098490.658
89_L138_V0.09830.656
117_L121_S0.098290.656
37_F135_L0.098160.655
88_L100_L0.097980.654
65_E73_K0.097390.650
84_L106_M0.097260.649
31_S36_F0.097230.649
26_S36_F0.097140.649
58_R122_V0.096680.645
88_L141_P0.096460.644
130_F137_G0.09620.642
4_L11_L0.095760.639
4_L12_A0.095660.639
79_L125_A0.095580.638
62_E65_E0.095350.637
92_L96_I0.09530.636
77_L90_E0.095230.636
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4apsA0.503513.80.903
4hfiA0.645412.70.904
4he8J0.51779.60.909
3l1lA0.43268.40.911
4hygA0.93627.90.912
3tlwA0.60996.60.915
2ksfA0.43265.40.918
4huqS0.836950.92
4humA13.70.924
3j09A0.4613.40.925
If you are interested in a protein containing this domain,
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