GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF1648 - Protein of unknown function (DUF1648)
Pfam: PF07853 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 51
Sequences: 560
Seq/Len: 10.98
HH_delta: 0.851 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
25_H33_D0.837473.681
27_N31_E0.729813.208
24_T36_G0.635362.793
11_T46_P0.477592.099
24_T34_G0.462612.033
32_P35_W0.41841.839
34_G41_G0.364641.603
24_T32_P0.327091.438
4_I7_P0.305891.344
44_L48_L0.303431.334
11_T15_Y0.298021.310
23_P32_P0.294681.295
36_G41_G0.28891.270
26_F32_P0.275171.209
10_I14_F0.274851.208
13_I16_P0.267851.177
15_Y38_K0.255791.124
3_I47_V0.237921.046
6_L26_F0.235261.034
11_T42_I0.235231.034
18_L42_I0.216710.953
17_Q37_S0.216240.950
25_H35_W0.210890.927
8_L43_F0.208390.916
14_F17_Q0.207670.913
20_D37_S0.206590.908
4_I11_T0.200810.883
28_A48_L0.197570.868
23_P36_G0.192960.848
41_G49_M0.185670.816
7_P16_P0.184040.809
4_I8_L0.183810.808
25_H34_G0.181790.799
24_T41_G0.181090.796
42_I46_P0.1810.796
21_Q37_S0.177910.782
5_V47_V0.175840.773
10_I16_P0.175530.772
15_Y35_W0.174830.768
46_P49_M0.171970.756
8_L36_G0.170020.747
3_I12_L0.165390.727
6_L14_F0.164470.723
7_P22_I0.16390.720
5_V49_M0.162490.714
28_A33_D0.162360.714
20_D31_E0.160150.704
6_L49_M0.159930.703
4_I49_M0.157770.693
21_Q48_L0.157070.690
27_N32_P0.152760.671
19_P33_D0.151230.665
3_I45_L0.150580.662
6_L39_S0.150340.661
10_I29_N0.149720.658
5_V13_I0.147240.647
27_N49_M0.146710.645
26_F49_M0.146190.643
13_I29_N0.145880.641
13_I17_Q0.145210.638
10_I46_P0.144850.637
9_I21_Q0.143070.629
22_I39_S0.140430.617
6_L13_I0.139770.614
24_T35_W0.137640.605
5_V10_I0.133020.585
23_P35_W0.132670.583
23_P43_F0.13080.575
30_G48_L0.129530.569
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3rfrA14.60.851
3arcH0.588230.863
4aq5E0.72552.90.863
3qkgA0.72552.90.864
1yewA0.98042.30.87
3hb3B0.86272.30.871
4aq5C0.84312.20.872
3m8lA0.82352.20.872
1kf6C0.98042.10.873
2gsmB0.88242.10.873
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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