GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF1772 - Domain of unknown function (DUF1772)
Pfam: PF08592 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 139
Sequences: 672
Seq/Len: 4.83
HH_delta: 0.911 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
89_I113_L0.189352.096
22_Y114_L0.176191.950
37_M41_S0.157121.739
26_W30_Y0.156891.737
90_N117_W0.156551.733
10_V14_L0.154341.708
42_L77_S0.151121.673
17_L21_E0.148041.639
6_F9_V0.146591.623
4_L39_P0.14281.581
19_P109_W0.13871.535
67_L134_L0.135241.497
36_F40_L0.134981.494
85_V120_L0.131161.452
4_L8_L0.130961.450
19_P134_L0.128431.422
36_F121_N0.127751.414
2_A5_A0.125161.385
2_A33_G0.121081.340
117_W121_N0.118531.312
89_I116_R0.118481.312
81_F86_N0.118111.307
133_L137_I0.117861.305
111_R115_D0.114421.267
62_P133_L0.113991.262
90_N113_L0.113981.262
109_W114_L0.113611.258
86_N120_L0.113091.252
26_W93_L0.111621.236
30_Y94_A0.108231.198
28_R32_R0.10691.183
13_A32_R0.105971.173
96_W108_D0.105561.168
33_G93_L0.105211.165
22_Y25_Q0.10481.160
82_T93_L0.104781.160
59_R68_W0.103261.143
9_V37_M0.10281.138
11_M14_L0.101861.128
86_N93_L0.101241.121
66_L70_A0.100891.117
49_L77_S0.100691.115
22_Y109_W0.099861.105
30_Y113_L0.098761.093
19_P114_L0.09851.090
5_A9_V0.098481.090
82_T90_N0.098321.088
6_F121_N0.098231.087
33_G38_P0.09811.086
66_L84_L0.097231.076
6_F10_V0.096621.070
30_Y33_G0.096621.070
82_T113_L0.096391.067
14_L26_W0.096151.064
29_F93_L0.095771.060
57_R65_R0.09491.050
13_A29_F0.094531.046
52_A72_A0.093521.035
96_W106_P0.093331.033
36_F74_L0.093041.030
132_F136_L0.092761.027
75_L88_P0.092451.023
3_F121_N0.092331.022
63_A137_I0.092311.022
26_W114_L0.092081.019
30_Y86_N0.091041.008
13_A25_Q0.090821.005
90_N120_L0.090681.004
71_A135_L0.090240.999
49_L112_A0.090110.997
26_W86_N0.090060.997
73_A111_R0.089760.994
80_P114_L0.089630.992
69_L72_A0.08960.992
102_P137_I0.089280.988
64_A131_A0.08910.986
17_L25_Q0.089030.986
34_P37_M0.08890.984
23_L73_A0.088120.975
61_R64_A0.088030.974
121_N132_F0.087730.971
7_S122_L0.086930.962
89_I120_L0.086920.962
50_Y68_W0.086680.960
82_T86_N0.085960.952
30_Y41_S0.085930.951
106_P109_W0.085680.948
62_P69_L0.085330.945
80_P84_L0.08510.942
59_R64_A0.085030.941
49_L88_P0.08480.939
114_L135_L0.084760.938
27_Q47_S0.08440.934
34_P40_L0.083670.926
91_N95_A0.082840.917
38_P44_S0.082810.917
77_S121_N0.082810.917
33_G81_F0.082690.915
112_A116_R0.082520.913
2_A37_M0.082490.913
37_M47_S0.082420.912
115_D133_L0.082260.911
45_A134_L0.081980.907
61_R112_A0.081740.905
74_L134_L0.081120.898
20_E66_L0.08070.893
35_R46_L0.080690.893
58_R134_L0.080620.892
30_Y82_T0.080150.887
82_T124_R0.079970.885
23_L27_Q0.079890.884
80_P129_L0.079810.883
23_L129_L0.079650.882
59_R136_L0.079620.881
31_R127_L0.079590.881
40_L128_S0.078540.869
24_K60_S0.078280.867
49_L61_R0.077980.863
24_K44_S0.077710.860
125_T131_A0.077520.858
16_S103_E0.077060.853
29_F91_N0.076620.848
27_Q122_L0.076570.848
26_W118_G0.076510.847
41_S83_F0.076380.845
87_V91_N0.076160.843
52_A123_V0.076070.842
61_R107_A0.076010.841
22_Y33_G0.075790.839
95_A130_V0.075770.839
52_A134_L0.07550.836
70_A76_L0.075370.834
111_R129_L0.075370.834
85_V133_L0.075270.833
74_L77_S0.075210.833
46_L115_D0.075170.832
49_L111_R0.074950.830
5_A29_F0.074680.827
74_L128_S0.074560.825
112_A115_D0.074420.824
40_L47_S0.074260.822
27_Q97_D0.074210.821
2_A79_I0.074080.820
78_I81_F0.073930.818
29_F125_T0.073770.817
78_I128_S0.07340.813
66_L92_R0.073360.812
7_S121_N0.073240.811
97_D137_I0.073170.810
61_R72_A0.073010.808
5_A8_L0.072990.808
51_L68_W0.072970.808
15_L19_P0.072960.808
6_F30_Y0.072910.807
19_P22_Y0.072890.807
126_V133_L0.07280.806
76_L95_A0.072680.805
51_L81_F0.072660.804
81_F89_I0.072510.803
23_L28_R0.072490.802
11_M117_W0.072410.802
52_A104_E0.072380.801
5_A25_Q0.072160.799
44_S63_A0.072110.798
70_A74_L0.072010.797
15_L114_L0.07190.796
38_P75_L0.071850.795
42_L46_L0.071840.795
82_T87_V0.071720.794
49_L76_L0.071640.793
84_L103_E0.071640.793
105_A111_R0.071610.793
104_E107_A0.071490.791
15_L111_R0.071460.791
96_W109_W0.071430.791
76_L115_D0.071360.790
49_L103_E0.071020.786
39_P135_L0.070810.784
3_F41_S0.07080.784
43_L47_S0.070710.783
103_E137_I0.070710.783
19_P51_L0.070140.776
75_L131_A0.069880.774
31_R116_R0.069840.773
9_V12_P0.069740.772
4_L10_V0.069660.771
103_E133_L0.06960.770
58_R133_L0.069540.770
108_D115_D0.06950.769
82_T120_L0.069440.769
60_S102_P0.069410.768
43_L126_V0.069090.765
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4gc0A0.798610.70.911
4dx5A0.834510.60.911
3ne5A0.978410.30.912
3mk7A0.956890.914
3s8fA0.91377.60.917
1v54A0.87776.60.919
2yevA0.899360.92
3w9iA0.98565.80.921
1fftA0.88495.40.922
2gsmA0.87774.50.925
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

Page generated in 0.0327 seconds.