GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Tic20 - Tic20-like protein
Pfam: PF09685 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 109
Sequences: 1006
Seq/Len: 9.23
HH_delta: 0.908 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
30_K33_K0.50552.748
50_T54_I0.472292.568
10_Y102_Y0.400912.180
6_A36_F0.393922.142
38_R41_A0.374152.034
10_Y40_H0.352931.919
11_L91_A0.33951.846
10_Y48_Q0.338141.838
58_L75_L0.309741.684
4_T8_L0.287411.563
81_L85_V0.285631.553
93_K98_E0.27131.475
38_R42_K0.269121.463
89_I93_K0.268791.461
89_I92_I0.253651.379
43_Q101_R0.246451.340
82_L86_L0.240491.308
39_F43_Q0.240091.305
27_W41_A0.239061.300
40_H94_A0.234531.275
47_F102_Y0.234311.274
18_L22_G0.233311.268
7_A95_N0.232181.262
61_L64_I0.230871.255
7_A11_L0.230721.254
9_A44_A0.230561.254
27_W31_K0.22721.235
80_W84_L0.226851.233
5_W26_V0.225361.225
10_Y90_G0.22441.220
50_T53_I0.217841.184
91_A95_N0.213371.160
87_S91_A0.207081.126
56_I60_I0.206331.122
7_A91_A0.205541.117
49_I52_L0.204691.113
85_V89_I0.203291.105
41_A44_A0.202821.103
25_I29_V0.196941.071
43_Q46_N0.196121.066
78_V81_L0.195091.061
27_W38_R0.1951.060
9_A37_V0.192231.045
42_K46_N0.190471.036
90_G102_Y0.189711.031
18_L21_I0.186651.015
9_A41_A0.185141.007
10_Y44_A0.18391.000
46_N50_T0.18220.991
28_I31_K0.181190.985
39_F99_P0.180130.979
62_S73_I0.180070.979
40_H43_Q0.179250.975
58_L61_L0.177690.966
58_L72_G0.176890.962
93_K100_Y0.17630.959
47_F86_L0.175270.953
74_L78_V0.175080.952
24_L28_I0.174410.948
31_K38_R0.174360.948
3_R7_A0.173530.943
58_L76_L0.173460.943
55_S80_W0.17340.943
47_F100_Y0.171860.934
73_I76_L0.168160.914
6_A44_A0.167820.912
71_I75_L0.166170.903
92_I96_K0.165670.901
22_G26_V0.164830.896
43_Q47_F0.163160.887
37_V44_A0.161690.879
93_K96_K0.160530.873
20_F23_P0.160510.873
19_G52_L0.159890.869
88_I92_I0.159210.866
21_I25_I0.153540.835
77_I80_W0.152690.830
19_G22_G0.150820.820
23_P41_A0.150370.818
58_L65_L0.147880.804
73_I77_I0.147720.803
54_I77_I0.146660.797
65_L74_L0.146370.796
64_I72_G0.146270.795
25_I28_I0.145580.791
40_H48_Q0.145530.791
22_G87_S0.145330.790
36_F43_Q0.144490.786
6_A37_V0.143380.780
92_I95_N0.142820.776
37_V49_I0.141980.772
30_K38_R0.141310.768
56_I92_I0.140860.766
11_L95_N0.140830.766
61_L71_I0.138640.754
72_G76_L0.138390.752
9_A86_L0.137780.749
29_V33_K0.137740.749
75_L79_L0.136940.745
54_I79_L0.136370.741
23_P44_A0.136350.741
54_I82_L0.135950.739
42_K90_G0.134450.731
44_A51_F0.133940.728
64_I71_I0.133420.725
22_G91_A0.133320.725
36_F41_A0.133130.724
28_I45_L0.132850.722
52_L84_L0.132610.721
11_L25_I0.132520.720
5_W30_K0.132270.719
60_I77_I0.131830.717
19_G48_Q0.131570.715
35_P38_R0.131340.714
42_K53_I0.130740.711
55_S61_L0.130140.708
57_I93_K0.129530.704
26_V33_K0.129280.703
51_F83_S0.129070.702
81_L90_G0.128850.701
58_L86_L0.128470.698
90_G100_Y0.12720.692
23_P102_Y0.127180.691
88_I98_E0.126850.690
44_A102_Y0.126730.689
22_G29_V0.126710.689
47_F90_G0.126480.688
37_V41_A0.126090.686
86_L90_G0.126090.686
23_P87_S0.125960.685
56_I59_F0.125840.684
90_G103_P0.125540.683
25_I85_V0.124530.677
45_L78_V0.12450.677
29_V32_D0.124280.676
40_H45_L0.124190.675
60_I81_L0.124170.675
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1vf5C0.34864.70.908
1zrtD0.33944.50.909
4h44C0.34862.90.916
3tijA0.58721.90.924
1cd1A0.33031.80.924
3zuxA0.40371.40.928
3l1lA0.88991.40.928
2yiuB0.35781.30.93
3s79A0.52291.30.93
3lb6C0.40371.30.93
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