GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF2147 - Uncharacterized protein conserved in bacteria (DUF2147)
Pfam: PF09917 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 114
Sequences: 604
Seq/Len: 5.3
HH_delta: 0.927 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
76_D79_D0.495533.383
100_C107_G0.474043.236
18_C23_C0.430792.941
22_Y69_W0.280021.912
102_G107_G0.27641.887
88_T96_K0.246491.683
58_L61_L0.235781.610
61_L87_I0.234561.601
74_I97_V0.227771.555
61_L85_A0.226321.545
85_A97_V0.226251.544
76_D108_K0.217461.484
2_L14_E0.215151.469
39_D42_N0.2121.447
5_T13_V0.21131.442
15_I58_L0.208851.426
17_K20_G0.206451.409
76_D83_Y0.204331.395
98_R109_S0.203241.387
96_K109_S0.201091.373
26_I52_L0.199971.365
6_P10_S0.194951.331
16_Y23_C0.192911.317
100_C103_I0.189331.292
98_R107_G0.188481.287
21_K62_K0.183621.253
74_I85_A0.182651.247
13_V24_G0.180581.233
47_L50_R0.179031.222
17_K22_Y0.175891.201
94_T113_T0.174141.189
45_G48_R0.17381.186
16_Y25_K0.172321.176
42_N75_Y0.170761.166
24_G58_L0.166141.134
89_L114_R0.164891.126
15_I74_I0.164151.121
42_N48_R0.162021.106
10_S26_I0.161971.106
79_D83_Y0.161911.105
103_I107_G0.161091.100
48_R75_Y0.160531.096
18_C107_G0.159751.091
44_D47_L0.158871.085
11_S28_W0.156961.071
19_G23_C0.154361.054
26_I54_G0.15091.030
14_E27_V0.149461.020
39_D44_D0.149341.019
50_R75_Y0.148911.017
5_T97_V0.148251.012
39_D43_P0.147381.006
62_K67_G0.14721.005
26_I57_I0.14661.001
18_C100_C0.144960.990
68_K88_T0.144860.989
73_K84_S0.143150.977
6_P110_Q0.143030.976
91_G94_T0.142360.972
44_D75_Y0.140850.962
93_D114_R0.140290.958
19_G113_T0.14010.956
15_I22_Y0.138840.948
23_C56_V0.136890.934
23_C107_G0.13630.930
98_R102_G0.134510.918
60_G90_S0.133990.915
46_A101_V0.133050.908
59_W73_K0.131960.901
23_C100_C0.131540.898
90_S96_K0.131510.898
21_K60_G0.130640.892
2_L28_W0.12990.887
50_R55_L0.129710.885
58_L85_A0.127930.873
2_L27_V0.127330.869
47_L55_L0.127290.869
78_E108_K0.126360.863
73_K82_T0.126120.861
13_V93_D0.1260.860
7_G10_S0.125730.858
14_E25_K0.125680.858
91_G97_V0.123320.842
2_L56_V0.121080.827
77_P99_G0.119980.819
6_P9_D0.119890.818
38_K41_K0.119420.815
26_I29_I0.11910.813
4_K113_T0.119030.813
79_D108_K0.1190.812
100_C105_L0.118980.812
69_W87_I0.118760.811
47_L75_Y0.118610.810
52_L55_L0.118170.807
69_W92_N0.117870.805
15_I89_L0.117790.804
4_K9_D0.116860.798
39_D75_Y0.11640.795
24_G97_V0.116290.794
56_V59_W0.115570.789
5_T110_Q0.114850.784
76_D99_G0.114430.781
81_K86_K0.113570.775
24_G110_Q0.113250.773
25_K69_W0.113150.772
20_G95_L0.112390.767
99_G107_G0.112380.767
96_K111_T0.112080.765
83_Y101_V0.111720.763
51_P54_G0.11120.759
58_L97_V0.11120.759
5_T8_G0.109730.749
16_Y56_V0.109540.748
5_T57_I0.109210.746
23_C85_A0.108730.742
10_S54_G0.108490.741
77_P108_K0.108210.739
8_G91_G0.107380.733
74_I99_G0.107340.733
45_G59_W0.107190.732
67_G113_T0.10660.728
44_D48_R0.10650.727
74_I112_W0.105750.722
86_K98_R0.105490.720
51_P60_G0.105340.719
88_T106_L0.104710.715
17_K23_C0.103980.710
24_G27_V0.103790.709
69_W80_G0.103550.707
46_A57_I0.10290.702
19_G26_I0.102570.700
8_G11_S0.102480.700
63_P68_K0.102480.700
18_C63_P0.102390.699
28_W39_D0.102140.697
65_G89_L0.102120.697
59_W85_A0.101850.695
13_V73_K0.101740.695
26_I77_P0.100610.687
9_D74_I0.100380.685
3_W15_I0.100150.684
38_K57_I0.099920.682
6_P43_P0.099610.680
7_G78_E0.098920.675
53_V69_W0.098780.674
25_K29_I0.09870.674
51_P73_K0.09820.670
88_T109_S0.098160.670
15_I51_P0.097940.669
87_I103_I0.097670.667
24_G98_R0.097540.666
10_S28_W0.097450.665
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1xhbA0.894711.10.927
1r76A0.903510.90.928
2x8sA0.47377.70.932
2ffuA0.90355.90.935
2d7iA0.89475.90.935
3jsyA0.57025.70.936
3glcA0.40355.10.937
1ei5A0.763250.937
3e7jA0.71934.70.938
1gxmA0.83334.60.938
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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