GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
GPDPase_memb - Membrane domain of glycerophosphoryl diester phosphodiesterase
Pfam: PF10110 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 149
Sequences: 705
Seq/Len: 4.73
HH_delta: 0.897 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
102_R128_T0.282863.144
125_W128_T0.256122.847
102_R125_W0.235692.620
34_R37_K0.188352.094
113_E123_E0.178751.987
41_P121_L0.160011.779
105_F110_I0.157861.755
34_R114_N0.156481.739
115_K119_E0.155391.727
106_V124_S0.148231.648
123_E127_L0.144971.611
103_L125_W0.135641.508
82_N85_L0.134141.491
128_T135_I0.127691.419
23_S91_L0.124241.381
109_L113_E0.123761.376
27_L31_A0.116741.298
67_S93_Y0.116531.295
106_V120_A0.1151.278
35_L49_Y0.112821.254
32_F140_L0.112611.252
124_S128_T0.108591.207
48_L122_K0.108371.205
52_L91_L0.108051.201
113_E127_L0.107891.199
65_L94_L0.1071.189
106_V121_L0.105661.174
30_T37_K0.104921.166
48_L83_P0.104841.165
28_L133_W0.104091.157
104_I139_L0.10211.135
50_F55_P0.101141.124
36_R136_L0.100321.115
55_P110_I0.10011.113
98_Y102_R0.098871.099
34_R40_G0.098491.095
116_S119_E0.097921.088
40_G137_G0.097351.082
13_I16_I0.096741.075
60_G68_K0.095651.063
43_N97_F0.09561.063
40_G44_L0.095311.059
42_Q59_L0.095061.057
36_R47_L0.09461.052
133_W137_G0.094581.051
21_K142_L0.094411.049
63_S68_K0.093951.044
49_Y66_L0.093221.036
104_I135_I0.093071.035
121_L142_L0.092951.033
110_I120_A0.092471.028
133_W141_L0.092181.025
99_L136_L0.092131.024
101_I136_L0.09191.022
18_R113_E0.091471.017
12_G22_I0.091351.015
33_K137_G0.091331.015
49_Y75_I0.090461.006
59_L89_Y0.090171.002
24_L132_F0.090151.002
49_Y68_K0.089280.992
18_R94_L0.088930.989
81_K87_I0.088850.988
121_L126_Q0.088460.983
22_I27_L0.088450.983
50_F75_I0.088210.981
78_Y81_K0.088150.980
19_G141_L0.088030.979
19_G139_L0.087940.978
51_L77_D0.087710.975
28_L140_L0.087550.973
57_A65_L0.086480.961
110_I117_F0.086360.960
98_Y101_I0.086010.956
52_L56_F0.085580.951
67_S119_E0.085570.951
101_I106_V0.084610.940
52_L80_M0.08380.931
46_F117_F0.083560.929
81_K85_L0.083410.927
26_S31_A0.08330.926
28_L113_E0.083110.924
21_K87_I0.083090.924
92_L99_L0.082770.920
106_V112_L0.082710.919
127_L134_R0.082550.918
98_Y109_L0.081850.910
25_R67_S0.08180.909
111_V123_E0.081360.904
43_N117_F0.081260.903
30_T131_R0.081120.902
47_L136_L0.08080.898
120_A124_S0.080650.896
107_L127_L0.08050.895
56_F94_L0.080180.891
13_I28_L0.080110.890
25_R43_N0.080070.890
102_R109_L0.080010.889
23_S122_K0.079740.886
53_I56_F0.078960.878
86_L93_Y0.078950.878
57_A66_L0.078770.876
46_F136_L0.078720.875
20_E27_L0.078480.872
59_L82_N0.078450.872
137_G141_L0.078450.872
38_L107_L0.078160.869
28_L137_G0.077970.867
101_I128_T0.077890.866
115_K120_A0.077870.866
48_L94_L0.077810.865
114_N119_E0.077550.862
38_L96_L0.07740.860
54_L84_W0.077120.857
104_I107_L0.077050.856
64_S137_G0.077040.856
39_F54_L0.076650.852
102_R130_G0.076230.847
92_L98_Y0.075990.845
96_L140_L0.075830.843
95_I124_S0.075770.842
36_R40_G0.075690.841
101_I109_L0.075650.841
14_Y112_L0.075440.839
78_Y82_N0.075410.838
24_L120_A0.075060.834
99_L141_L0.075060.834
41_P110_I0.074670.830
43_N93_Y0.074650.830
76_T122_K0.07460.829
52_L76_T0.074470.828
131_R134_R0.074040.823
98_Y107_L0.073870.821
46_F97_F0.07370.819
54_L91_L0.073540.817
37_K117_F0.073410.816
12_G27_L0.073370.816
55_P66_L0.073320.815
15_R35_L0.073310.815
76_T87_I0.073240.814
132_F141_L0.073180.813
122_K126_Q0.07310.813
83_P91_L0.072790.809
46_F52_L0.072660.808
38_L112_L0.072580.807
23_S92_L0.072210.803
55_P67_S0.07210.801
75_I78_Y0.071950.800
112_L122_K0.071860.799
95_I131_R0.071780.798
30_T60_G0.071750.798
76_T85_L0.071520.795
92_L96_L0.071410.794
103_L139_L0.071220.792
109_L127_L0.071090.790
135_I138_R0.071090.790
64_S76_T0.070840.787
39_F108_P0.070790.787
23_S33_K0.070690.786
37_K110_I0.070670.786
19_G57_A0.070630.785
85_L142_L0.070350.782
60_G63_S0.07030.781
42_Q100_N0.070010.778
33_K93_Y0.069960.778
43_N115_K0.069960.778
121_L132_F0.069820.776
31_A42_Q0.069780.776
44_L51_L0.06970.775
28_L40_G0.069630.774
109_L115_K0.069620.774
25_R96_L0.069570.773
26_S140_L0.069560.773
54_L75_I0.069530.773
104_I134_R0.069440.772
85_L136_L0.069340.771
98_Y120_A0.069340.771
96_L122_K0.069170.769
90_L93_Y0.068960.767
13_I81_K0.068920.766
40_G134_R0.068810.765
136_L140_L0.068810.765
14_Y108_P0.06880.765
16_I89_Y0.068770.764
17_L26_S0.06870.764
115_K123_E0.068460.761
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2lnlA0.771818.30.897
3oduA0.865880.912
3pblA0.80545.60.917
3rzeA0.77854.20.922
2h88D0.67793.70.924
4iarA0.77853.50.925
3uonA0.79872.90.927
3w9iA0.85232.60.929
3arcZ0.38262.30.931
3ne5A0.83892.20.931
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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