GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
OpgC_C - OpgC protein
Pfam: PF10129 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0316
Length: 358
Sequences: 3804
Seq/Len: 10.63
HH_delta: 0.959 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
75_A79_Y0.460313.665
141_Y145_L0.400873.192
302_L306_H0.395923.153
52_G204_L0.384723.064
6_D305_R0.379053.018
21_I318_S0.322272.566
49_Y207_G0.308562.457
10_G304_G0.298942.380
137_I141_Y0.286252.279
12_A42_G0.280892.237
81_A312_C0.250721.996
55_Y65_W0.249791.989
17_F310_V0.249511.987
71_L149_P0.235831.878
202_L278_A0.232491.851
14_V18_I0.232331.850
88_L313_V0.227541.812
7_F296_W0.222531.772
16_I40_A0.219431.747
10_G303_L0.214741.710
50_A54_A0.214211.706
70_R145_L0.210391.675
306_H310_V0.20781.655
12_A39_A0.20541.636
41_E199_L0.202881.616
298_R301_I0.200751.599
136_D141_Y0.200181.594
44_V140_L0.199131.586
227_A276_A0.198551.581
225_W229_A0.192261.531
67_A71_L0.189681.510
81_A309_P0.189091.506
2_D49_Y0.188551.501
139_P143_V0.184551.470
105_L108_E0.18431.468
202_L274_F0.182851.456
148_A204_L0.181541.446
8_F42_G0.179241.427
10_G13_L0.178341.420
79_Y83_I0.177781.416
78_L308_L0.174221.387
77_Q80_V0.1741.386
20_H47_S0.169871.353
104_D107_W0.169821.352
6_D301_I0.16761.335
10_G300_L0.167371.333
44_V47_S0.167131.331
110_N113_P0.167121.331
68_T72_W0.166721.328
148_A200_F0.166031.322
196_W199_L0.165551.318
136_D139_P0.165291.316
218_P222_W0.164271.308
49_Y210_W0.164081.307
131_Q134_Y0.163941.305
80_V145_L0.163341.301
56_G208_W0.162741.296
188_G192_N0.162021.290
141_Y308_L0.160751.280
110_N116_E0.158531.262
110_N115_F0.158361.261
44_V77_Q0.158351.261
58_R69_R0.157551.255
70_R77_Q0.157451.254
40_A77_Q0.156441.246
41_E196_W0.155921.242
58_R73_R0.154951.234
224_V228_V0.154881.233
14_V303_L0.153391.221
288_G292_L0.15311.219
302_L305_R0.153011.218
89_A316_V0.152131.211
52_G148_A0.152091.211
51_A54_A0.152061.211
10_G307_S0.15191.210
54_A58_R0.150681.200
314_G318_S0.149511.191
5_I46_L0.149061.187
2_D5_I0.148071.179
52_G207_G0.147511.175
20_H314_G0.147341.173
190_F196_W0.147241.172
51_A145_L0.147171.172
190_F193_P0.146261.165
234_A276_A0.146061.163
141_Y144_L0.145981.162
22_P25_V0.145511.159
138_L142_I0.145271.157
140_L144_L0.144831.153
82_H135_L0.144191.148
78_L307_S0.143581.143
110_N114_L0.142991.139
103_P106_L0.142781.137
112_G116_E0.142571.135
297_L300_L0.142381.134
40_A311_F0.141591.127
85_L313_V0.141481.127
77_Q141_Y0.141461.126
188_G194_F0.140781.121
16_I20_H0.140691.120
178_L181_P0.138721.105
144_L148_A0.138581.104
54_A65_W0.138141.100
144_L200_F0.138111.100
44_V141_Y0.137681.096
58_R65_W0.13661.088
303_L310_V0.136421.086
53_L57_R0.136381.086
69_R72_W0.135571.080
45_F206_L0.135481.079
6_D9_R0.135431.078
233_F237_W0.134731.073
40_A145_L0.134581.072
160_W164_A0.133931.066
51_A55_Y0.133011.059
136_D143_V0.132781.057
85_L89_A0.132711.057
223_L226_L0.131331.046
70_R80_V0.129871.034
7_F300_L0.129421.031
47_S200_F0.128771.025
57_R60_R0.128691.025
80_V308_L0.128631.024
145_L149_P0.128571.024
201_V205_W0.127461.015
55_Y142_I0.127281.014
82_H308_L0.127241.013
72_W76_W0.127131.012
222_W225_W0.126871.010
17_F314_G0.126831.010
76_W79_Y0.126611.008
144_L149_P0.126491.007
316_V319_L0.12611.004
170_W201_V0.125440.999
70_R307_S0.125380.998
13_L141_Y0.125350.998
142_I200_F0.125030.996
70_R141_Y0.124760.993
41_E315_V0.124690.993
167_V171_L0.123680.985
75_A142_I0.123660.985
6_D82_H0.122870.978
137_I145_L0.121770.970
69_R73_R0.12120.965
201_V204_L0.120810.962
40_A44_V0.120620.960
77_Q81_A0.12030.958
140_L149_P0.119850.954
47_S50_A0.119820.954
10_G309_P0.119710.953
46_L51_A0.119340.950
16_I137_I0.11880.946
50_A53_L0.118430.943
12_A16_I0.118330.942
311_F315_V0.118120.941
73_R77_Q0.11810.940
209_G213_G0.11810.940
140_L143_V0.117870.939
296_W299_P0.117770.938
44_V136_D0.117260.934
44_V314_G0.116860.931
43_F74_R0.116750.930
38_D234_A0.116670.929
70_R148_A0.116250.926
47_S145_L0.116240.926
234_A238_R0.116170.925
169_L172_A0.116040.924
52_G56_G0.115650.921
8_F46_L0.115610.921
51_A142_I0.115350.919
141_Y148_A0.115310.918
199_L274_F0.11530.918
233_F236_F0.11530.918
70_R308_L0.115270.918
111_L115_F0.115130.917
103_P107_W0.114890.915
134_Y311_F0.114530.912
230_Y276_A0.114410.911
13_L310_V0.113990.908
79_Y110_N0.11340.903
10_G14_V0.113090.901
51_A148_A0.113070.900
9_R138_L0.112860.899
286_P290_R0.112790.898
10_G306_H0.112770.898
5_I50_A0.112510.896
136_D145_L0.11240.895
142_I145_L0.112140.893
56_G60_R0.112120.893
103_P108_E0.112050.892
223_L227_A0.112040.892
276_A279_Y0.111870.891
80_V141_Y0.111650.889
59_F72_W0.11160.889
55_Y148_A0.110730.882
53_L207_G0.11060.881
204_L208_W0.11060.881
178_L232_L0.110590.881
84_A94_A0.110310.878
136_D140_L0.109960.876
66_A69_R0.109720.874
15_M39_A0.109560.872
140_L308_L0.109470.872
52_G208_W0.109050.868
16_I47_S0.108880.867
112_G115_F0.108720.866
131_Q141_Y0.108540.864
190_F195_A0.108350.863
77_Q308_L0.108330.863
72_W75_A0.108310.862
109_F114_L0.108080.861
226_L229_A0.108020.860
300_L304_G0.107560.856
6_D78_L0.107220.854
161_L185_S0.107220.854
133_G136_D0.106880.851
77_Q145_L0.106770.850
44_V137_I0.106490.848
10_G42_G0.105910.843
200_F304_G0.105630.841
122_L134_Y0.105530.840
78_L200_F0.105510.840
81_A85_L0.105440.840
145_L148_A0.105220.838
228_V233_F0.105180.838
308_L312_C0.104710.834
44_V50_A0.104690.834
198_L201_V0.104680.834
299_P303_L0.103970.828
47_S80_V0.103910.827
6_D199_L0.103260.822
137_I196_W0.103170.822
77_Q136_D0.103140.821
137_I140_L0.103080.821
304_G308_L0.102740.818
85_L312_C0.102640.817
192_N195_A0.102630.817
214_R222_W0.102580.817
44_V70_R0.102370.815
9_R141_Y0.102170.814
164_A167_V0.101790.811
13_L50_A0.101680.810
205_W209_G0.101060.805
77_Q309_P0.100770.802
301_I305_R0.100740.802
304_G307_S0.100550.801
142_I149_P0.100430.800
20_H44_V0.100220.798
13_L17_F0.100160.798
89_A320_A0.100140.797
51_A70_R0.100110.797
318_S322_Q0.100090.797
139_P145_L0.100060.797
2_D210_W0.099910.796
170_W175_I0.099640.793
171_L174_Q0.099450.792
88_L216_F0.099380.791
228_V231_V0.099330.791
137_I143_V0.09930.791
51_A200_F0.09860.785
50_A144_L0.098350.783
107_W110_N0.098280.783
39_A42_G0.098250.782
60_R232_L0.09820.782
41_E193_P0.098190.782
135_L139_P0.098180.782
23_G27_E0.0980.780
76_W306_H0.097940.780
46_L133_G0.097890.779
111_L114_L0.097860.779
190_F194_F0.097840.779
147_L193_P0.09780.779
109_F113_P0.097670.778
136_D314_G0.097530.777
122_L131_Q0.09750.776
50_A70_R0.097480.776
150_L154_L0.097160.774
15_M235_F0.097150.774
113_P117_D0.097050.773
220_R321_G0.096940.772
109_F112_G0.09690.772
6_D304_G0.096840.771
78_L82_H0.096810.771
9_R46_L0.096730.770
193_P196_W0.096620.769
16_I82_H0.096420.768
19_D41_E0.096360.767
113_P116_E0.096210.766
47_S137_I0.09610.765
6_D50_A0.096050.765
230_Y233_F0.096050.765
142_I148_A0.096010.765
104_D109_F0.095970.764
229_A232_L0.095920.764
122_L125_I0.09560.761
309_P313_V0.095450.760
44_V199_L0.095430.760
189_W193_P0.095340.759
12_A40_A0.095260.759
37_S273_H0.09510.757
45_F141_Y0.095040.757
112_G117_D0.094950.756
40_A141_Y0.094940.756
68_T230_Y0.094880.756
174_Q178_L0.094690.754
123_V127_L0.09460.753
157_R216_F0.094320.751
98_L104_D0.094130.750
35_G39_A0.094010.749
2_D292_L0.093950.748
223_L278_A0.093890.748
17_F176_F0.093690.746
233_F324_V0.093640.746
59_F311_F0.093620.745
6_D191_F0.093530.745
279_Y283_W0.093520.745
6_D51_A0.093510.745
88_L317_L0.093510.745
74_R311_F0.093450.744
79_Y135_L0.093440.744
83_I87_L0.093380.744
215_R219_R0.09330.743
166_S174_Q0.093270.743
19_D35_G0.09320.742
74_R78_L0.092840.739
57_R156_R0.092830.739
5_I9_R0.092750.739
212_R215_R0.092680.738
81_A84_A0.092620.738
41_E314_G0.09260.737
60_R223_L0.092270.735
89_A319_L0.092270.735
82_H86_F0.092250.735
206_L278_A0.092130.734
6_D73_R0.092090.733
161_L172_A0.091760.731
50_A308_L0.091610.729
47_S51_A0.091150.726
298_R305_R0.091150.726
45_F203_G0.091130.726
7_F304_G0.091080.725
73_R142_I0.090870.724
71_L142_I0.090830.723
13_L80_V0.090760.723
227_A283_W0.090440.720
41_E142_I0.090420.720
9_R43_F0.090370.720
59_F65_W0.090310.719
137_I142_I0.090280.719
6_D46_L0.089950.716
47_S70_R0.089920.716
108_E117_D0.089880.716
277_L281_V0.089760.715
316_V320_A0.089740.715
13_L303_L0.089670.714
317_L321_G0.089580.713
6_D200_F0.089560.713
90_L303_L0.08940.712
159_P219_R0.08940.712
85_L135_L0.089360.712
13_L16_I0.089350.711
19_D133_G0.08930.711
165_V169_L0.089290.711
72_W153_W0.088880.708
198_L271_L0.088830.707
74_R145_L0.088790.707
85_L317_L0.088760.707
144_L204_L0.088440.704
153_W157_R0.088440.704
109_F116_E0.088430.704
80_V144_L0.08840.704
47_S77_Q0.088390.704
93_I105_L0.088220.702
210_W213_G0.08820.702
35_G40_A0.088190.702
212_R305_R0.088060.701
40_A43_F0.088020.701
98_L165_V0.087830.699
193_P197_Q0.087740.699
12_A17_F0.087720.699
161_L164_A0.087720.699
49_Y82_H0.087520.697
39_A46_L0.087370.696
185_S188_G0.087290.695
42_G81_A0.087270.695
16_I44_V0.087230.695
73_R80_V0.087160.694
5_I129_R0.087080.693
7_F301_I0.087060.693
157_R160_W0.087060.693
84_A88_L0.087050.693
170_W174_Q0.086980.693
25_V127_L0.086970.693
65_W206_L0.086970.693
51_A204_L0.086920.692
109_F117_D0.086890.692
72_W202_L0.086820.691
227_A280_L0.086720.691
82_H189_W0.086540.689
292_L301_I0.086540.689
44_V49_Y0.086430.688
12_A19_D0.086340.688
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1cmxA0.15645.90.959
4b19A0.08383.60.963
2h3oA0.15922.90.964
4httA0.63692.50.965
4hygA0.34362.20.967
2m67A0.18991.80.968
1rklA0.10061.60.969
3tlwA0.26261.50.97
2latA0.08661.40.97
2cfqA0.18721.40.97
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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