GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
L_HGMIC_fpl - Lipoma HMGIC fusion partner-like protein
Pfam: PF10242 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0375
Length: 181
Sequences: 1429
Seq/Len: 7.9
HH_delta: 0.943 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
44_C55_C0.326593.038
22_S157_A0.294292.738
20_F77_V0.229952.139
17_V21_I0.228172.123
110_G117_G0.20651.921
75_F79_I0.190561.773
138_Q141_G0.185061.722
24_Y37_S0.183981.712
13_A84_L0.177091.648
27_G155_G0.166891.553
91_S109_C0.166681.551
13_A85_L0.156751.458
11_C27_G0.153591.429
41_F74_A0.150461.400
78_G82_V0.149421.390
9_S87_I0.142951.330
82_V86_L0.141051.312
20_F74_A0.140711.309
152_C156_W0.140531.307
128_P131_W0.138471.288
139_L148_K0.137191.276
9_S113_Q0.137111.276
80_G120_L0.136771.272
23_P42_R0.134861.255
30_E33_P0.134561.252
90_L95_C0.133131.239
7_L11_C0.132811.236
47_Q108_I0.130761.217
21_I24_Y0.130551.215
77_V95_C0.130271.212
126_L131_W0.127551.187
73_A128_P0.127191.183
21_I87_I0.126581.178
133_S156_W0.126421.176
80_G151_D0.125831.171
18_V22_S0.124691.160
82_V120_L0.12451.158
38_F43_R0.12391.153
117_G126_L0.123551.149
36_G45_S0.12351.149
61_S64_D0.122541.140
41_F80_G0.122131.136
18_V21_I0.1221.135
154_L158_Y0.120771.124
108_I116_A0.120731.123
48_M59_A0.119361.110
82_V151_D0.119051.108
80_G86_L0.118981.107
96_C102_S0.117981.098
127_Y131_W0.117891.097
14_I18_V0.11771.095
20_F93_F0.117521.093
127_Y158_Y0.116051.080
80_G116_A0.113871.059
52_E56_G0.113811.059
15_L89_L0.112771.049
22_S39_G0.112731.049
81_C90_L0.111911.041
114_F118_L0.111291.035
64_D117_G0.111171.034
146_P150_G0.110621.029
23_P39_G0.11051.028
79_I82_V0.110241.026
77_V120_L0.109731.021
14_I79_I0.109561.019
16_C84_L0.109081.015
90_L112_L0.108831.012
19_S158_Y0.108541.010
115_V118_L0.107951.004
20_F39_G0.107621.001
128_P154_L0.107260.998
16_C77_V0.107110.996
109_C152_C0.106840.994
26_L38_F0.106220.988
20_F24_Y0.106090.987
101_C114_F0.105970.986
135_E138_Q0.105770.984
88_A99_S0.105620.983
99_S112_L0.105480.981
30_E50_E0.105180.979
71_K96_C0.105040.977
13_A47_Q0.104610.973
70_W95_C0.10460.973
94_S102_S0.104080.968
14_I28_G0.103370.962
53_Q57_G0.103310.961
13_A87_I0.102830.957
38_F62_F0.102460.953
35_S135_E0.102420.953
11_C17_V0.101290.942
107_K111_W0.101190.941
130_G133_S0.101020.940
64_D149_L0.100950.939
39_G48_M0.100870.938
135_E147_Y0.100180.932
129_A158_Y0.099860.929
76_F156_W0.099780.928
127_Y141_G0.099380.925
109_C120_L0.099320.924
91_S130_G0.098940.920
18_V81_C0.098850.920
27_G37_S0.09880.919
111_W114_F0.098690.918
157_A160_L0.098690.918
132_D135_E0.09860.917
153_S159_Y0.098490.916
111_W115_V0.097860.910
86_L92_L0.097830.910
45_S76_F0.097760.910
147_Y150_G0.097370.906
27_G64_D0.097360.906
127_Y132_D0.097270.905
54_E61_S0.0970.902
8_L55_C0.096960.902
23_P44_C0.096850.901
24_Y156_W0.096710.900
17_V81_C0.096630.899
83_L90_L0.09640.897
19_S161_A0.096230.895
53_Q56_G0.096190.895
91_S151_D0.096160.895
78_G98_R0.0960.893
131_W149_L0.095670.890
107_K120_L0.095630.890
82_V89_L0.095330.887
29_S56_G0.094730.881
66_P85_L0.094590.880
54_E57_G0.094310.877
82_V88_A0.094250.877
156_W159_Y0.094150.876
79_I86_L0.094130.876
29_S153_S0.093950.874
56_G59_A0.093860.873
109_C113_Q0.093720.872
26_L120_L0.093710.872
9_S35_S0.093560.870
78_G104_S0.093240.867
126_L130_G0.093120.866
11_C83_L0.0930.865
40_L82_V0.092860.864
58_Y89_L0.092650.862
73_A134_P0.092270.858
19_S157_A0.09220.858
52_E59_A0.092050.856
108_I114_F0.09190.855
129_A132_D0.09170.853
14_I21_I0.091680.853
17_V48_M0.09150.851
103_R151_D0.091180.848
8_L54_E0.091070.847
39_G54_E0.090940.846
63_G153_S0.090940.846
14_I17_V0.090620.843
74_A152_C0.090460.842
119_C135_E0.09030.840
39_G44_C0.090110.838
14_I95_C0.089750.835
62_F137_R0.089720.835
90_L109_C0.089680.834
97_F102_S0.089370.831
14_I160_L0.089270.831
49_D52_E0.08920.830
104_S115_V0.089020.828
131_W136_V0.088890.827
10_L90_L0.08850.823
113_Q159_Y0.088250.821
112_L116_A0.087970.818
48_M54_E0.087910.818
95_C118_L0.087830.817
73_A113_Q0.087750.816
59_A64_D0.087710.816
83_L112_L0.087560.815
91_S106_F0.087370.813
92_L97_F0.086720.807
131_W137_R0.086620.806
141_G146_P0.086560.805
104_S107_K0.086540.805
79_I115_V0.08620.802
142_P145_D0.08620.802
27_G149_L0.086070.801
67_S120_L0.085910.799
33_P50_E0.085870.799
84_L102_S0.085660.797
71_K118_L0.085060.791
135_E141_G0.085020.791
34_Y56_G0.084550.787
78_G106_F0.084440.786
35_S87_I0.084080.782
137_R141_G0.084030.782
72_A115_V0.084020.782
32_T93_F0.083960.781
7_L84_L0.083890.780
146_P149_L0.083880.780
9_S111_W0.083730.779
29_S134_P0.083610.778
101_C105_V0.083540.777
87_I113_Q0.083360.776
112_L115_V0.08330.775
34_Y52_E0.08320.774
89_L93_F0.082950.772
38_F87_I0.08270.769
51_W63_G0.082440.767
99_S108_I0.082170.764
127_Y154_L0.081890.762
20_F95_C0.081880.762
27_G147_Y0.081850.761
82_V112_L0.081630.759
32_T119_C0.081580.759
28_G36_G0.081550.759
52_E149_L0.081520.758
8_L43_R0.081420.757
8_L88_A0.081410.757
24_Y95_C0.081380.757
7_L10_L0.081130.755
49_D78_G0.081080.754
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1xrdA0.204460.943
1q8dA0.37024.80.945
3j2wE0.25414.40.947
3rlfG0.57464.30.947
2gfpA0.3374.20.947
3rkoL0.55254.20.947
1jb0M0.13263.10.95
4ht2A0.320430.95
3kg2A0.60222.70.951
1jd0A0.31492.70.951
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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