GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF2752 - Protein of unknown function (DUF2752)
Pfam: PF10825 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 52
Sequences: 431
Seq/Len: 8.29
HH_delta: 0.873 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
28_D31_A0.529052.751
5_K11_P0.428482.228
4_F8_T0.419592.182
17_M39_G0.36551.901
22_I26_H0.346751.803
19_R35_Y0.33731.754
24_L29_F0.321761.673
32_A41_L0.288981.503
33_F37_P0.2881.498
4_F10_I0.280931.461
23_A28_D0.26981.403
20_A40_L0.250841.304
23_A35_Y0.247551.287
11_P14_G0.233311.213
17_M21_F0.232771.210
39_G44_P0.218481.136
20_A43_L0.213541.110
18_T22_I0.209331.089
18_T49_L0.208871.086
17_M20_A0.207911.081
45_F48_L0.207891.081
17_M43_L0.206341.073
29_F44_P0.199421.037
14_G46_F0.194311.010
8_T15_C0.179210.932
24_L46_F0.179030.931
33_F40_L0.175410.912
24_L28_D0.174290.906
43_L46_F0.174170.906
39_G43_L0.171850.894
20_A28_D0.171630.893
23_A31_A0.168980.879
21_F40_L0.168110.874
41_L47_L0.167560.871
21_F43_L0.166120.864
32_A40_L0.165870.863
11_P17_M0.161670.841
20_A24_L0.161490.840
25_L46_F0.160480.835
25_L34_R0.159960.832
6_A47_L0.157280.818
4_F41_L0.157180.817
28_D34_R0.156890.816
14_G43_L0.155790.810
18_T36_N0.154570.804
2_C12_C0.151750.789
1_P41_L0.151160.786
34_R37_P0.149480.777
1_P33_F0.149120.775
13_P36_N0.146810.763
27_G31_A0.145950.759
1_P18_T0.145250.755
6_A20_A0.144030.749
11_P39_G0.142470.741
11_P18_T0.142190.739
17_M40_L0.141160.734
23_A33_F0.140090.728
19_R33_F0.139480.725
38_L48_L0.138930.722
44_P47_L0.138330.719
13_P32_A0.137450.715
20_A35_Y0.136870.712
25_L44_P0.136710.711
16_G36_N0.136680.711
20_A38_L0.135620.705
42_L48_L0.134690.700
3_P7_L0.134580.700
44_P48_L0.133120.692
5_K25_L0.132930.691
42_L49_L0.131860.686
35_Y40_L0.130880.681
32_A44_P0.130420.678
3_P38_L0.12920.672
30_A45_F0.12890.670
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3k1lB0.51929.80.873
3pwfA0.570.88
1lkoA0.53856.70.881
3cw2K0.46156.50.882
3alrA0.80775.60.885
1neeA0.46155.50.886
2zt5A0.80775.40.886
2gagD0.86545.20.886
1k82A0.71154.90.888
1yuzA0.46154.30.891
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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