GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF2892 - Protein of unknown function (DUF2892)
Pfam: PF11127 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 66
Sequences: 1182
Seq/Len: 17.91
HH_delta: 0.858 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
14_I47_G1.200743.933
19_V35_L0.624822.046
13_R46_T0.616532.019
17_G40_G0.585621.918
13_R50_G0.570681.869
12_V55_Y0.535371.753
23_L36_L0.524951.719
9_D55_Y0.519211.700
24_G37_G0.515341.688
9_D13_R0.463421.518
51_F56_A0.455971.493
50_G55_Y0.402831.319
45_V49_T0.385561.263
28_L34_W0.379771.244
15_I54_L0.376371.233
27_G33_G0.374421.226
18_I44_L0.364981.195
9_D46_T0.362241.186
34_W38_F0.361831.185
46_T55_Y0.357331.170
21_L41_A0.35271.155
14_I44_L0.351921.153
18_I22_A0.350861.149
28_L33_G0.316391.036
10_R50_G0.312781.024
56_A59_G0.309371.013
24_G33_G0.305741.001
29_F32_W0.30240.990
51_F54_L0.297730.975
13_R55_Y0.295690.968
11_I15_I0.289540.948
16_I54_L0.279950.917
35_L39_V0.275970.904
54_L58_L0.273750.897
55_Y59_G0.273610.896
25_L29_F0.271990.891
12_V16_I0.269260.882
7_T11_I0.260640.854
39_V43_L0.259820.851
24_G28_L0.256140.839
45_V48_I0.253010.829
7_T10_R0.246880.809
27_G34_W0.243220.797
42_M46_T0.238870.782
15_I56_A0.23510.770
17_G47_G0.233360.764
24_G27_G0.232570.762
8_T55_Y0.2320.760
11_I54_L0.231960.760
19_V39_V0.228390.748
19_V27_G0.226890.743
33_G37_G0.223970.734
9_D47_G0.221830.727
16_I39_V0.221510.725
8_T11_I0.219160.718
42_M45_V0.218110.714
20_L47_G0.216180.708
20_L40_G0.215830.707
24_G29_F0.212530.696
53_P56_A0.210470.689
21_L44_L0.210030.688
8_T12_V0.20990.687
22_A25_L0.209760.687
35_L38_F0.207920.681
17_G21_L0.207510.680
22_A26_L0.203930.668
19_V23_L0.203120.665
36_L43_L0.20310.665
37_G41_A0.199580.654
41_A45_V0.198790.651
25_L28_L0.198630.651
43_L46_T0.197240.646
13_R47_G0.197210.646
21_L34_W0.195350.640
18_I32_W0.192830.632
20_L36_L0.192430.630
28_L49_T0.191350.627
10_R25_L0.187980.616
24_G40_G0.187250.613
16_I20_L0.186810.612
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1p58A0.757611.40.858
3j27A0.78794.40.882
4azxA0.78794.30.882
1sdoA0.40913.20.889
2ghvE0.363630.889
4hytB0.98482.40.895
3oymA0.95452.30.896
1h5wA0.33331.80.901
3r3tA0.33331.70.903
3noqA0.33331.70.903
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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