GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF2905 - Protein of unknown function (DUF2905)
Pfam: PF11146 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 64
Sequences: 329
Seq/Len: 5.14
HH_delta: 0.886 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
37_R42_T0.570443.460
58_S62_N0.459832.789
60_L64_F0.376332.283
10_L13_I0.298431.810
5_L12_L0.276761.679
26_G39_G0.253791.540
57_L61_L0.251921.528
32_G48_T0.251281.524
38_R41_F0.244191.481
35_R42_T0.238381.446
6_I17_L0.224471.362
51_I55_V0.221381.343
39_G42_T0.217431.319
5_L19_L0.215651.308
10_L14_V0.214451.301
6_I13_I0.212221.287
27_L49_S0.212181.287
48_T52_L0.208991.268
15_L53_L0.207961.262
2_G19_L0.207961.262
35_R52_L0.190541.156
8_I36_I0.186291.130
45_F49_S0.186071.129
45_F50_S0.185141.123
2_G20_P0.183741.115
50_S61_L0.181471.101
25_F60_L0.180571.095
6_I10_L0.178381.082
35_R44_Y0.176981.074
20_P29_R0.170671.035
1_M23_G0.170081.032
52_L63_L0.170061.032
1_M20_P0.169921.031
19_L52_L0.169191.026
1_M19_L0.167941.019
6_I38_R0.1661.007
59_L62_N0.162880.988
25_F29_R0.162010.983
41_F62_N0.161030.977
18_L56_V0.15860.962
36_I39_G0.154280.936
8_I12_L0.152280.924
5_L59_L0.151420.919
16_G54_S0.150440.913
50_S62_N0.149910.909
7_V10_L0.149870.909
11_I15_L0.149170.905
36_I52_L0.147410.894
35_R48_T0.146310.888
17_L63_L0.14310.868
23_G49_S0.141620.859
4_W20_P0.140980.855
49_S63_L0.136620.829
50_S55_V0.135070.819
7_V63_L0.132870.806
29_R32_G0.131870.800
58_S61_L0.129630.786
3_K21_W0.127830.775
57_L60_L0.127370.773
2_G8_I0.125790.763
7_V14_V0.124630.756
4_W60_L0.124060.753
5_L11_I0.123820.751
4_W48_T0.123610.750
1_M21_W0.123510.749
2_G16_G0.1230.746
20_P24_K0.122830.745
24_K40_N0.122580.744
9_G16_G0.121840.739
4_W8_I0.120430.731
13_I61_L0.120160.729
1_M26_G0.120150.729
41_F61_L0.120090.728
32_G49_S0.120090.728
24_K38_R0.120.728
12_L51_I0.118880.721
16_G39_G0.115710.702
14_V60_L0.115310.700
30_L48_T0.115210.699
11_I56_V0.115170.699
28_G49_S0.113930.691
8_I51_I0.112740.684
22_L27_L0.112340.681
35_R49_S0.111760.678
35_R56_V0.111080.674
13_I55_V0.110010.667
2_G9_G0.109640.665
45_F58_S0.109450.664
14_V57_L0.109160.662
2_G58_S0.108920.661
44_Y49_S0.108370.657
15_L50_S0.107060.649
52_L61_L0.106440.646
34_I59_L0.10640.645
37_R53_L0.105790.642
4_W7_V0.105610.641
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2gsmA0.859415.30.886
4ev6A0.843812.90.89
2iubA0.84388.20.898
1zoyC0.90627.80.899
4i0uA0.8756.70.902
1fftA0.78125.70.905
2wdqC0.93754.70.909
1v54A0.78123.30.915
3s8fA0.76562.90.917
3nafA0.57812.80.917
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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