GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF3077 - Protein of unknown function (DUF3077)
Pfam: PF11275 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 79
Sequences: 438
Seq/Len: 5.54
HH_delta: 0.908 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
40_A64_S0.455272.976
33_A71_V0.374522.448
18_F32_H0.29451.925
26_C74_A0.284931.862
42_H51_E0.245141.602
17_L24_I0.239191.563
30_L71_V0.229231.498
46_E56_M0.224361.466
44_T64_S0.221431.447
16_P51_E0.218061.425
26_C77_G0.210171.374
23_G73_D0.205941.346
47_A57_A0.201991.320
37_L67_A0.193591.265
28_D67_A0.191721.253
37_L57_A0.181121.184
48_A57_A0.177591.161
42_H60_A0.170241.113
50_S53_D0.169111.105
70_L74_A0.166641.089
56_M70_L0.164821.077
33_A74_A0.163631.070
36_L62_Y0.160421.049
50_S57_A0.159651.044
23_G63_L0.158221.034
58_W69_A0.156311.022
49_M59_A0.155731.018
34_S68_K0.155491.016
18_F58_W0.155031.013
36_L67_A0.154961.013
34_S69_A0.154151.008
29_A36_L0.153811.005
68_K72_D0.153191.001
42_H55_R0.151010.987
38_G55_R0.150690.985
20_V23_G0.149610.978
32_H59_A0.149510.977
43_L60_A0.14830.969
36_L68_K0.146790.959
44_T71_V0.146730.959
61_H66_M0.146370.957
19_R24_I0.145990.954
21_N57_A0.145810.953
20_V49_M0.143250.936
25_P41_R0.142080.929
36_L66_M0.140560.919
35_V69_A0.13870.907
17_L28_D0.138420.905
36_L63_L0.138060.902
25_P28_D0.137320.898
39_C47_A0.136450.892
39_C59_A0.132290.865
67_A77_G0.132080.863
27_E54_R0.131850.862
39_C72_D0.13140.859
19_R44_T0.130150.851
21_N45_Y0.128790.842
65_E68_K0.128330.839
17_L70_L0.127960.836
46_E55_R0.127560.834
20_V38_G0.127350.832
40_A67_A0.126940.830
31_E45_Y0.125070.817
20_V70_L0.123760.809
39_C57_A0.123550.808
54_R74_A0.121920.797
32_H36_L0.121120.792
49_M65_E0.120030.785
63_L67_A0.119970.784
62_Y66_M0.1190.778
32_H69_A0.118750.776
59_A66_M0.118670.776
33_A37_L0.118660.776
45_Y61_H0.118330.773
23_G52_E0.118220.773
51_E54_R0.117440.768
24_I28_D0.116460.761
22_P26_C0.116120.759
28_D71_V0.11540.754
45_Y53_D0.114360.747
15_H38_G0.114070.746
19_R51_E0.11390.744
43_L64_S0.113710.743
22_P72_D0.111970.732
23_G45_Y0.111780.731
27_E76_L0.111610.730
54_R76_L0.111130.726
37_L44_T0.110790.724
46_E54_R0.110680.723
42_H46_E0.110460.722
43_L53_D0.109960.719
39_C46_E0.109420.715
27_E31_E0.109240.714
60_A77_G0.10920.714
27_E35_V0.10890.712
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1rblM0.89878.50.908
3rbnA0.88617.90.91
3zxwB0.91146.70.912
1svdM0.89876.70.912
1gk8I0.89876.40.913
1wddS0.898760.914
3eegA0.97475.60.915
1j7xA0.5575.40.915
4ad8A0.46845.30.916
1ytmA0.87344.80.918
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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