GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF2798 - Protein of unknown function (DUF2798)
Pfam: PF11391 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 60
Sequences: 616
Seq/Len: 10.27
HH_delta: 0.791 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
39_P43_P0.490692.639
4_S38_W0.405282.180
8_S34_W0.39822.142
11_M15_M0.370891.995
52_V56_V0.36461.961
35_L39_P0.361621.945
7_M11_M0.33711.813
28_S32_K0.294571.585
11_M41_A0.289361.557
17_L26_F0.284911.533
45_S49_A0.259981.398
3_M11_M0.247851.333
7_M41_A0.238461.283
3_M37_A0.224791.209
46_L50_P0.223621.203
27_F31_L0.221951.194
2_I56_V0.220321.185
15_M45_S0.208821.123
49_A53_R0.208741.123
50_P54_K0.207211.115
31_L35_L0.198161.066
27_F32_K0.197371.062
48_V56_V0.197291.061
3_M49_A0.192581.036
4_S30_W0.188371.013
8_S14_V0.185050.995
17_L22_F0.183260.986
24_D32_K0.181850.978
24_D57_E0.17990.968
6_M33_A0.178440.960
3_M7_M0.175690.945
5_F9_L0.175570.944
15_M37_A0.174530.939
8_S41_A0.174010.936
51_L58_R0.173550.934
2_I59_L0.168550.907
33_A40_V0.168320.905
4_S37_A0.168010.904
10_I44_I0.166760.897
31_L51_L0.166240.894
30_W34_W0.166230.894
47_I51_L0.163810.881
9_L34_W0.162840.876
16_T20_V0.162020.872
13_F25_G0.161640.869
5_F45_S0.157830.849
50_P53_R0.157760.849
9_L13_F0.157360.846
28_S31_L0.157310.846
6_M9_L0.156960.844
54_K58_R0.15440.831
13_F30_W0.154090.829
29_R51_L0.152430.820
35_L43_P0.152310.819
10_I15_M0.150190.808
10_I53_R0.150150.808
12_S50_P0.148450.799
45_S53_R0.148280.798
9_L31_L0.147970.796
13_F35_L0.147640.794
19_N32_K0.146830.790
12_S43_P0.144450.777
20_V27_F0.144160.775
6_M10_I0.141620.762
6_M49_A0.139770.752
17_L27_F0.1390.748
8_S15_M0.138840.747
5_F8_S0.138840.747
28_S47_I0.138290.744
12_S37_A0.137150.738
40_V44_I0.136890.736
4_S34_W0.13440.723
24_D27_F0.134370.723
28_S39_P0.133210.717
9_L55_L0.133060.716
4_S11_M0.132630.713
7_M14_V0.132260.711
22_F26_F0.130410.701
30_W37_A0.129730.698
16_T59_L0.1270.683
4_S45_S0.1270.683
11_M18_L0.126640.681
25_G54_K0.125940.677
13_F16_T0.125480.675
13_F38_W0.124910.672
20_V29_R0.124650.671
24_D29_R0.123880.666
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4aw6A0.933327.10.791
4il3A13.30.86
3w9iA0.98332.30.87
3ne5A0.98332.30.87
4dx5A0.98332.30.87
4httA0.93331.70.877
2v50A0.98331.60.879
2kr6A0.98331.20.888
3tijA0.366710.891
4b4aA0.933310.892
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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