GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
O-antigen_lig - O-antigen ligase like membrane protein
Pfam: PF13425 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0499
Length: 140
Sequences: 4148
Seq/Len: 29.63
HH_delta: 0.918 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
92_I125_L1.156384.419
95_N100_W1.106584.229
100_W104_N0.871763.331
128_Y132_G0.853063.260
123_D127_E0.85293.259
125_L133_L0.70632.699
63_F66_R0.608522.325
85_W122_L0.601612.299
88_A117_P0.596742.280
124_I136_F0.596282.279
117_P123_D0.555862.124
88_A122_L0.51611.972
84_I118_H0.514581.966
102_F128_Y0.501991.918
119_N122_L0.486861.860
89_W93_K0.471671.802
100_W126_L0.461431.763
90_Q93_K0.454261.736
131_I135_L0.453981.735
85_W119_N0.423241.617
92_I130_I0.416851.593
19_Q24_I0.391211.495
105_F127_E0.383941.467
133_L137_L0.378181.445
91_Y100_W0.375061.433
88_A92_I0.369891.413
91_Y126_L0.36871.409
116_S123_D0.366341.400
88_A126_L0.364691.394
26_A30_V0.363211.388
86_K90_Q0.362021.383
101_G127_E0.356891.364
131_I134_I0.352731.348
84_I117_P0.343981.314
92_I96_P0.343751.314
118_H123_D0.338711.294
91_Y94_E0.333541.275
124_I133_L0.332261.270
124_I128_Y0.331761.268
117_P120_G0.315971.207
20_S23_A0.311891.192
88_A105_F0.308481.179
7_V11_L0.308351.178
93_K96_P0.308161.178
11_L14_A0.307791.176
117_P126_L0.305961.169
95_N98_F0.305091.166
88_A118_H0.30151.152
82_I86_K0.298451.140
31_L35_F0.292581.118
13_I17_L0.291721.115
21_R78_M0.284531.087
79_S82_I0.282681.080
103_G127_E0.280561.072
92_I131_I0.279881.070
75_D79_S0.27941.068
15_L23_A0.279341.067
22_T26_A0.27881.065
120_G124_I0.276981.058
94_E100_W0.275931.054
120_G123_D0.271331.037
15_L18_T0.271021.036
77_S82_I0.27021.033
98_F131_I0.264791.012
85_W118_H0.261180.998
22_T25_I0.257890.985
15_L27_L0.252360.964
128_Y131_I0.25060.958
87_Y90_Q0.24720.945
89_W92_I0.24450.934
130_I134_I0.241020.921
90_Q94_E0.238490.911
80_G84_I0.237060.906
104_N127_E0.236730.905
92_I126_L0.235590.900
25_I78_M0.234310.895
83_E86_K0.233520.892
120_G136_F0.232330.888
76_S80_G0.232270.888
105_F123_D0.232090.887
9_L13_I0.232050.887
12_L27_L0.231580.885
78_M82_I0.226730.866
91_Y105_F0.226550.866
96_P130_I0.226170.864
78_M85_W0.224890.859
121_Y133_L0.224050.856
121_Y137_L0.21970.840
121_Y125_L0.217280.830
134_I138_I0.216490.827
87_Y91_Y0.21540.823
39_K42_I0.21470.820
92_I133_L0.213720.817
40_K44_L0.213660.816
76_S79_S0.213230.815
52_V55_A0.211540.808
105_F117_P0.211360.808
62_P65_S0.210240.803
125_L131_I0.20720.792
91_Y95_N0.207010.791
91_Y108_Y0.204140.780
97_L130_I0.20120.769
33_I36_L0.198770.760
105_F126_L0.198370.758
44_L49_G0.195570.747
32_L36_L0.193250.738
106_G123_D0.192220.735
8_I12_L0.189490.724
21_R66_R0.188590.721
79_S83_E0.188260.719
116_S120_G0.188240.719
40_K43_K0.186910.714
36_L44_L0.183820.702
85_W116_S0.183750.702
44_L48_L0.181910.695
123_D126_L0.180910.691
19_Q118_H0.180030.688
74_S83_E0.178650.683
93_K130_I0.178350.682
103_G128_Y0.177870.680
92_I121_Y0.176770.675
39_K43_K0.176420.674
20_S81_R0.175150.669
20_S24_I0.173310.662
12_L16_F0.17290.661
87_Y113_N0.172070.658
22_T100_W0.17020.650
14_A18_T0.169080.646
22_T102_F0.1690.646
9_L54_I0.16870.645
50_I53_I0.168660.645
116_S119_N0.168440.644
40_K109_S0.168280.643
107_Y112_S0.168060.642
46_L49_G0.168020.642
7_V10_L0.167920.642
118_H128_Y0.167680.641
57_F73_S0.167450.640
77_S80_G0.165770.633
107_Y110_T0.164760.630
102_F105_F0.162270.620
104_N116_S0.161270.616
88_A125_L0.161250.616
44_L47_V0.161170.616
55_A74_S0.161030.615
43_K55_A0.160750.614
122_L125_L0.159640.610
9_L46_L0.159180.608
114_Y117_P0.158780.607
102_F117_P0.158460.606
38_F44_L0.15790.603
70_A76_S0.157490.602
106_G115_N0.157140.600
38_F58_I0.156780.599
103_G106_G0.156660.599
64_F68_F0.156630.599
11_L41_R0.155980.596
101_G105_F0.155780.595
26_A33_I0.15550.594
106_G118_H0.155340.594
125_L128_Y0.155310.593
11_L15_L0.155110.593
50_I55_A0.154280.590
28_F32_L0.154190.589
121_Y136_F0.15390.588
56_L62_P0.153160.585
102_F127_E0.152230.582
57_F60_S0.151940.581
87_Y108_Y0.151810.580
34_F136_F0.151630.579
83_E112_S0.150470.575
32_L35_F0.150050.573
59_F135_L0.150030.573
32_L43_K0.149480.571
95_N126_L0.149380.571
17_L62_P0.148940.569
23_A118_H0.148860.569
21_R26_A0.148550.568
30_V34_F0.14820.566
27_L30_V0.147150.562
23_A114_Y0.146850.561
85_W117_P0.146270.559
21_R127_E0.145930.558
53_I65_S0.145570.556
104_N115_N0.145380.556
14_A117_P0.14410.551
21_R79_S0.143960.550
45_L48_L0.143890.550
9_L56_L0.143870.550
22_T123_D0.143790.549
77_S128_Y0.143280.548
10_L79_S0.142960.546
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3rceA0.94293.40.918
2k21A0.51433.40.918
4azxD0.32.30.925
3j27B0.32.30.925
1p58D0.32.10.926
3giaA0.62141.80.928
3qf4A0.951.80.928
3l1lA0.53571.80.929
3hxiC0.151.60.931
3qf4B0.951.50.931
If you are interested in a protein containing this domain,
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