GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DoxX_2 - DoxX-like family
Pfam: PF13564 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0131
Length: 103
Sequences: 2382
Seq/Len: 23.13
HH_delta: 0.902 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
7_A49_A0.87533.258
17_K45_E0.848763.159
51_G66_A0.5862.181
11_L49_A0.581082.163
10_F70_L0.558152.077
47_L51_G0.532311.981
18_L42_G0.4821.794
7_A53_L0.479841.786
39_Y43_V0.462781.722
14_G49_A0.457721.704
28_F38_V0.438681.633
14_G46_I0.389741.451
12_F16_M0.366261.363
36_W40_V0.363571.353
27_M30_K0.360951.343
65_L69_G0.359181.337
27_M31_L0.358631.335
3_T55_P0.343521.278
15_V19_F0.342111.273
17_K41_V0.337981.258
74_M77_A0.337911.258
40_V44_L0.323611.204
61_R64_P0.314941.172
45_E73_L0.314561.171
48_G70_L0.314431.170
51_G69_G0.308141.147
15_V46_I0.305411.137
50_I54_I0.299571.115
55_P61_R0.289781.078
72_V76_G0.287761.071
62_L69_G0.281871.049
20_G23_E0.280121.043
66_A69_G0.278031.035
9_F12_F0.277411.032
77_A81_H0.27731.032
21_P39_Y0.276761.030
41_V76_G0.276391.029
80_T84_A0.272551.014
8_L12_F0.271771.011
63_S67_A0.268671.000
63_S70_L0.265030.986
73_L76_G0.263590.981
22_P26_E0.263010.979
14_G42_G0.260150.968
37_F41_V0.259260.965
26_E30_K0.255960.953
7_A11_L0.252820.941
5_L8_L0.251230.935
12_F20_G0.248960.927
41_V73_L0.248210.924
13_S31_L0.245020.912
79_Y82_L0.244360.909
21_P38_V0.243980.908
13_S17_K0.24380.907
41_V44_L0.243660.907
13_S45_E0.240760.896
16_M20_G0.238850.889
7_A13_S0.236860.882
5_L9_F0.236610.881
78_I82_L0.236360.880
11_L53_L0.235290.876
44_L73_L0.233820.870
49_A53_L0.232030.864
36_W39_Y0.230320.857
67_A71_L0.2260.841
28_F32_G0.225710.840
23_E27_M0.225010.837
36_W47_L0.224830.837
5_L26_E0.22420.834
16_M19_F0.222130.827
4_I55_P0.220620.821
44_L69_G0.219870.818
80_T83_R0.219140.816
24_M38_V0.218110.812
54_I85_G0.213630.795
62_L65_L0.211330.787
51_G63_S0.210880.785
35_K39_Y0.210850.785
51_G62_L0.209520.780
71_L76_G0.209080.778
35_K50_I0.208560.776
4_I8_L0.207230.771
24_M28_F0.203740.758
28_F31_L0.199820.744
16_M24_M0.199450.742
3_T41_V0.198140.737
6_L72_V0.197320.734
35_K38_V0.196290.731
33_Y80_T0.195280.727
21_P24_M0.194550.724
17_K42_G0.193120.719
53_L61_R0.192760.717
33_Y37_F0.192280.716
55_P62_L0.191330.712
24_M27_M0.191160.711
28_F33_Y0.189750.706
68_L72_V0.187740.699
23_E26_E0.18720.697
2_L80_T0.185460.690
64_P76_G0.18130.675
24_M45_E0.180040.670
46_I50_I0.178710.665
4_I7_A0.177490.661
66_A72_V0.177030.659
10_F63_S0.176060.655
32_G74_M0.175560.653
6_L65_L0.175130.652
33_Y79_Y0.174590.650
64_P67_A0.172930.644
42_G66_A0.172550.642
61_R65_L0.172470.642
71_L75_L0.171910.640
19_F67_A0.171710.639
41_V45_E0.171660.639
3_T63_S0.171340.638
33_Y55_P0.170580.635
5_L75_L0.170370.634
9_F81_H0.169870.632
24_M30_K0.169520.631
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2l0eA0.32042.20.902
3k3fA0.81551.90.905
2iubA0.54371.50.911
4ev6A0.54371.40.912
2nq2A0.92231.10.916
4g1uA0.922310.92
2looA0.72820.90.92
4i0uA0.5340.90.92
2qi9A0.92230.70.925
3rceA0.95150.70.926
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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