GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
SdpI - SdpIYhfL protein family
Pfam: PF13630 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 76
Sequences: 412
Seq/Len: 5.42
HH_delta: 0.878 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
5_P20_D0.36782.879
27_H34_F0.299242.342
37_G67_A0.217381.701
16_T27_H0.210781.650
30_A34_F0.208431.631
20_D24_K0.190621.492
13_T16_T0.188261.473
11_Y16_T0.177831.392
57_I61_L0.171871.345
37_G63_I0.164951.291
11_Y27_H0.159461.248
1_P22_N0.157871.236
1_P9_I0.147341.153
67_A71_S0.146851.149
18_K22_N0.145361.138
36_I39_I0.142011.112
19_S22_N0.141891.111
15_W75_S0.140051.096
68_L76_Y0.139851.095
12_R16_T0.139631.093
54_N73_I0.138711.086
1_P31_G0.136931.072
59_I62_L0.136911.072
1_P41_L0.135181.058
43_I60_I0.13481.055
42_L62_L0.134621.054
18_K66_I0.13371.046
40_V66_I0.133471.045
2_K13_T0.133031.041
66_I69_I0.132381.036
40_V44_I0.132241.035
11_Y26_A0.130091.018
2_K5_P0.128381.005
25_K31_G0.128231.004
26_A75_S0.127731.000
24_K59_I0.125990.986
20_D46_I0.125970.986
6_N72_I0.12580.985
11_Y76_Y0.125760.984
12_R29_F0.125720.984
47_I61_L0.125110.979
22_N74_Y0.125070.979
65_L69_I0.124940.978
35_I68_L0.124790.977
45_G48_I0.123820.969
36_I41_L0.12270.960
13_T23_W0.12210.956
41_L58_L0.121580.952
12_R23_W0.121490.951
58_L65_L0.121190.949
62_L66_I0.120540.943
11_Y34_F0.118530.928
57_I70_I0.118490.927
28_R38_G0.118480.927
19_S63_I0.117890.923
9_I61_L0.117460.919
3_K13_T0.117440.919
28_R39_I0.116590.913
55_W68_L0.116250.910
29_F70_I0.116130.909
30_A33_I0.116130.909
5_P12_R0.116110.909
26_A74_Y0.115660.905
7_S13_T0.115610.905
6_N10_G0.114360.895
45_G60_I0.113460.888
17_M27_H0.113370.887
19_S39_I0.112380.880
63_I66_I0.112320.879
31_G74_Y0.111540.873
10_G23_W0.111390.872
68_L71_S0.111390.872
19_S47_I0.10950.857
44_I56_I0.109270.855
33_I71_S0.1080.845
13_T22_N0.107980.845
22_N48_I0.107660.843
49_L61_L0.107380.840
7_S18_K0.106740.835
3_K59_I0.105920.829
13_T72_I0.105920.829
58_L62_L0.105290.824
1_P4_K0.104930.821
8_W74_Y0.10440.817
24_K47_I0.104380.817
2_K9_I0.103940.814
12_R44_I0.103670.811
19_S66_I0.103660.811
54_N65_L0.103650.811
15_W26_A0.103530.810
2_K24_K0.103480.810
3_K36_I0.103050.807
48_I62_L0.102970.806
12_R17_M0.10290.805
25_K75_S0.102670.804
62_L73_I0.102270.800
2_K11_Y0.102220.800
46_I72_I0.102210.800
2_K7_S0.101990.798
37_G41_L0.10180.797
35_I39_I0.101790.797
59_I70_I0.101540.795
43_I55_W0.101440.794
25_K64_I0.10130.793
59_I66_I0.101250.792
13_T18_K0.101220.792
3_K20_D0.100710.788
31_G34_F0.100450.786
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2pusA0.342112.80.878
2xq2A0.85536.10.894
2wwbA0.84215.80.894
1oq1A0.36844.80.898
2ksdA0.73684.60.899
2q17A0.34214.20.901
3dinC0.93423.90.902
3zuxA0.81583.70.904
2yzcA0.39473.20.906
3pjzA0.72373.10.906
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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