GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF4190 - Domain of unknown function (DUF4190)
Pfam: PF13828 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 62
Sequences: 755
Seq/Len: 12.18
HH_delta: 0.824 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
22_V26_L0.924413.072
23_A52_G0.867462.883
43_G47_A0.851192.829
28_H53_Y0.753172.503
46_I50_V0.680932.263
3_I7_V0.677772.253
31_L42_R0.612192.035
9_G51_L0.590361.962
6_L10_I0.583811.940
5_S48_G0.552451.836
9_G48_G0.542751.804
4_A8_L0.540011.795
6_L44_M0.482291.603
2_A41_G0.446441.484
31_L46_I0.440671.465
9_G23_A0.432511.438
27_G49_I0.420331.397
53_Y57_V0.395381.314
24_I53_Y0.382671.272
4_A26_L0.368941.226
29_I33_Q0.360111.197
5_S27_G0.34941.161
54_I58_L0.346211.151
28_H32_R0.338321.124
49_I53_Y0.332751.106
25_I29_I0.331931.103
24_I52_G0.324311.078
50_V54_I0.307951.024
33_Q39_Q0.302471.005
34_I39_Q0.291620.969
3_I44_M0.28970.963
42_R46_I0.289690.963
30_A34_I0.287310.955
28_H49_I0.286460.952
24_I28_H0.285840.950
32_R36_R0.285610.949
34_I37_S0.267090.888
34_I41_G0.25950.862
21_I56_I0.257740.857
8_L22_V0.255990.851
48_G52_G0.254410.846
5_S30_A0.24620.818
4_A22_V0.241530.803
12_G20_G0.237120.788
40_R59_A0.233450.776
6_L47_A0.233230.775
12_G55_G0.212230.705
24_I49_I0.211950.704
17_G20_G0.208410.693
23_A51_L0.207990.691
18_L22_V0.20460.680
31_L35_R0.201390.669
31_L49_I0.200340.666
15_L19_L0.199330.663
20_G52_G0.19770.657
27_G52_G0.197470.656
9_G16_C0.195470.650
2_A30_A0.189360.629
31_L34_I0.188660.627
19_L57_V0.187730.624
20_G55_G0.178280.593
44_M51_L0.174650.580
11_L36_R0.174480.580
17_G59_A0.173070.575
19_L22_V0.169420.563
47_A51_L0.168750.561
27_G48_G0.168690.561
18_L56_I0.167120.555
18_L50_V0.164830.548
10_I54_I0.162290.539
2_A38_G0.161760.538
41_G45_A0.161380.536
51_L54_I0.161030.535
18_L21_I0.160910.535
55_G59_A0.159930.532
45_A48_G0.158560.527
24_I45_A0.157940.525
4_A33_Q0.156220.519
30_A57_V0.153760.511
35_R42_R0.153060.509
18_L59_A0.152640.507
13_L31_L0.150970.502
22_V29_I0.150750.501
26_L49_I0.149160.496
13_L20_G0.148930.495
32_R53_Y0.146890.488
8_L19_L0.146080.486
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4humA110.70.824
3w4tA14.80.848
3mktA0.98394.80.848
2k1kA0.46774.20.852
2hi7B0.56453.90.854
1ciiA0.70973.90.854
2ljbA0.43553.70.856
1pi7A0.58063.60.856
2qi9A13.60.856
2kihA0.43553.60.856
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