GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
PGG - Domain of unknown function
Pfam: PF13962 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 113
Sequences: 696
Seq/Len: 6.16
HH_delta: 0.921 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
20_T28_T0.262662.286
58_S104_V0.254792.218
15_A70_I0.206671.799
4_L67_L0.204961.784
56_L110_I0.204491.780
6_D9_N0.196261.708
11_L73_L0.1921.671
67_L71_F0.179271.560
19_A67_L0.177041.541
3_W7_T0.169861.478
27_F59_N0.166141.446
24_Q28_T0.164741.434
27_F33_Y0.164541.432
59_N110_I0.159061.384
21_V103_M0.157071.367
84_L87_Y0.153121.333
31_G41_G0.150191.307
58_S101_S0.148051.289
62_A75_S0.145881.270
34_W44_I0.143591.250
36_D39_D0.143531.249
12_L70_I0.143441.249
88_L98_A0.141311.230
43_P74_I0.140631.224
31_G66_S0.13881.208
49_P53_K0.138171.203
7_T11_L0.137281.195
61_I104_V0.137271.195
43_P107_A0.135891.183
2_K6_D0.135271.177
12_L16_T0.135141.176
59_N105_A0.134631.172
61_I105_A0.133961.166
25_A59_N0.133061.158
11_L74_I0.131821.147
7_T77_L0.131421.144
13_V16_T0.131231.142
18_I36_D0.129771.130
32_G41_G0.128461.118
72_L93_V0.126371.100
14_V92_S0.125631.093
49_P61_I0.125181.090
51_A112_L0.1241.079
26_A59_N0.123431.074
29_P106_F0.122891.070
22_T62_A0.122581.067
36_D41_G0.122441.066
45_L49_P0.120821.052
41_G55_F0.120721.051
43_P87_Y0.119331.039
48_K86_R0.117671.024
59_N106_F0.117641.024
105_A110_I0.117571.023
36_D40_A0.116531.014
70_I86_R0.114180.994
33_Y39_D0.113670.989
24_Q52_F0.113160.985
58_S106_F0.113040.984
23_F26_A0.1130.984
68_A88_L0.112740.981
16_T21_V0.111590.971
34_W40_A0.110970.966
41_G52_F0.110840.965
15_A35_Q0.110580.962
105_A108_A0.109090.950
10_S14_V0.10850.944
61_I98_A0.107580.936
10_S18_I0.107480.936
32_G44_I0.107430.935
34_W41_G0.107040.932
54_A111_Y0.1070.931
28_T52_F0.106450.927
6_D112_L0.106250.925
9_N42_T0.106190.924
71_F106_F0.106090.923
28_T76_G0.105680.920
20_T95_M0.105070.915
60_T110_I0.104990.914
71_F83_F0.103720.903
8_R58_S0.102850.895
18_I75_S0.102630.893
27_F41_G0.10260.893
20_T30_P0.102010.888
63_F70_I0.101970.888
11_L29_P0.101590.884
18_I62_A0.101260.881
19_A22_T0.101030.879
21_V62_A0.10090.878
28_T42_T0.100770.877
32_G45_L0.100740.877
54_A108_A0.100720.877
27_F45_L0.100220.872
73_L102_M0.100160.872
29_P95_M0.099930.870
26_A103_M0.098990.862
51_A56_L0.098970.861
63_F108_A0.098620.858
72_L91_A0.098570.858
8_R74_I0.098140.854
67_L75_S0.098110.854
2_K36_D0.097840.852
8_R29_P0.097480.848
18_I97_I0.097230.846
13_V83_F0.097050.845
41_G44_I0.0970.844
72_L96_W0.096870.843
24_Q63_F0.096320.838
33_Y63_F0.096160.837
29_P69_A0.096010.836
43_P58_S0.0960.836
17_L21_V0.095880.835
16_T70_I0.095730.833
45_L69_A0.095730.833
44_I72_L0.095630.832
15_A19_A0.094980.827
46_A51_A0.094940.826
99_L109_G0.094840.825
65_S97_I0.094430.822
14_V108_A0.093860.817
54_A105_A0.093830.817
85_R89_L0.093830.817
73_L91_A0.093820.817
28_T88_L0.093530.814
65_S84_L0.093470.814
31_G52_F0.09340.813
75_S81_R0.093240.812
12_L83_F0.093050.810
40_A63_F0.093040.810
67_L103_M0.092930.809
53_K82_R0.092790.808
23_F110_I0.092140.802
56_L101_S0.091690.798
57_I97_I0.090710.790
74_I85_R0.090070.784
92_S106_F0.089720.781
27_F70_I0.08940.778
72_L105_A0.088840.773
25_A62_A0.088810.773
9_N86_R0.088660.772
35_Q70_I0.088640.772
20_T98_A0.088290.768
20_T25_A0.088130.767
49_P82_R0.087960.766
88_L92_S0.087830.764
58_S84_L0.087620.763
26_A62_A0.087570.762
2_K104_V0.087510.762
45_L99_L0.08740.761
15_A65_S0.087020.757
21_V39_D0.086790.755
24_Q42_T0.086640.754
19_A107_A0.086630.754
77_L99_L0.086420.752
31_G43_P0.086410.752
96_W100_I0.086240.751
9_N13_V0.085840.747
62_A86_R0.085790.747
40_A109_G0.085450.744
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2iubA0.601813.60.921
4ev6A0.601813.60.921
4i0uA0.60189.90.925
2a65A0.99125.70.933
3ayfA0.91155.60.933
3lmaA0.45134.70.935
1jh4B0.23014.70.935
2vv5A0.93812.90.941
3o7qA0.87612.20.944
4h44B0.97352.20.944
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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