GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
RSN1_TM - Late exocytosis associated with Golgi transport
Pfam: PF13967 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 157
Sequences: 776
Seq/Len: 4.94
HH_delta: 0.948 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
105_N139_H0.328983.530
89_I150_V0.264062.834
52_G55_G0.207242.224
45_P48_L0.201032.157
65_D77_Y0.17491.877
98_L102_L0.168641.810
92_F149_Y0.161011.728
87_I91_L0.147471.583
44_R48_L0.147181.579
152_Y156_R0.145911.566
15_V19_L0.14371.542
97_S146_F0.142411.528
6_L10_L0.136241.462
83_L121_L0.13561.455
85_M153_L0.133281.430
70_R129_V0.132481.422
64_S70_R0.131851.415
107_T135_R0.131011.406
68_I72_C0.128321.377
135_R138_A0.126281.355
33_P36_Y0.124741.339
147_T151_L0.124441.335
104_I138_A0.122721.317
144_Y148_F0.121021.299
9_N12_I0.119621.284
15_V57_I0.118181.268
11_I15_V0.117681.263
14_L42_P0.11721.258
69_L77_Y0.116741.253
63_I69_L0.116611.251
95_I99_P0.116411.249
12_I83_L0.115421.239
29_R72_C0.115361.238
58_K62_K0.115111.235
60_V132_G0.113981.223
44_R71_H0.11351.218
27_F30_I0.112491.207
82_F86_L0.112271.205
101_L124_L0.110911.190
81_R121_L0.110181.182
83_L127_S0.108891.169
100_V103_P0.108881.168
93_L148_F0.108421.163
102_L106_Y0.108221.161
46_P49_P0.107691.156
30_I33_P0.107491.153
144_Y147_T0.106971.148
73_G76_A0.106481.143
4_T98_L0.105391.131
109_G112_D0.104181.118
80_L143_A0.103951.115
11_I14_L0.103741.113
124_L128_N0.102561.101
44_R47_P0.101651.091
142_F148_F0.101421.088
93_L146_F0.101251.087
17_L21_C0.099861.072
148_F152_Y0.099861.072
13_F34_R0.099381.066
22_I52_G0.099271.065
141_V144_Y0.098671.059
21_C57_I0.096171.032
137_W154_L0.095961.030
11_I152_Y0.095831.028
147_T154_L0.095671.027
30_I104_I0.095651.026
66_D87_I0.095451.024
102_L124_L0.095421.024
122_D135_R0.09491.018
60_V73_G0.094431.013
91_L104_I0.09321.000
16_L60_V0.093050.999
9_N105_N0.092810.996
91_L95_I0.092430.992
68_I80_L0.092410.992
96_L142_F0.092290.990
51_R126_I0.092180.989
25_K49_P0.092080.988
30_I46_P0.09160.983
64_S67_E0.091250.979
82_F103_P0.090790.974
52_G59_P0.090610.972
49_P155_W0.090360.970
53_F57_I0.089990.966
89_I106_Y0.089870.964
97_S142_F0.089720.963
20_F80_L0.08970.963
17_L22_I0.089530.961
48_L152_Y0.08920.957
108_G136_L0.088650.951
7_A11_I0.08770.941
130_P145_I0.087550.940
25_K140_V0.087270.937
14_L152_Y0.087020.934
54_F57_I0.086970.933
133_S140_V0.086960.933
120_G129_V0.086730.931
76_A80_L0.086110.924
86_L90_F0.085740.920
63_I76_A0.085380.916
4_T94_S0.084870.911
134_S140_V0.084580.908
108_G128_N0.084560.907
63_I72_C0.084060.902
4_T137_W0.083710.898
15_V99_P0.083710.898
25_K153_L0.083580.897
22_I25_K0.083270.894
31_Y74_L0.083060.891
5_S8_I0.082670.887
137_W150_V0.082640.887
16_L72_C0.082510.885
35_S85_M0.08230.883
2_F19_L0.082070.881
14_L134_S0.082050.880
79_F88_K0.081690.877
3_L6_L0.081670.876
53_F104_I0.081530.875
109_G124_L0.081250.872
31_Y63_I0.081230.872
60_V79_F0.081170.871
26_R35_S0.080640.865
11_I153_L0.080250.861
137_W141_V0.080210.861
10_L95_I0.08010.860
77_Y99_P0.080060.859
96_L145_I0.079830.857
122_D128_N0.079620.854
2_F12_I0.079370.852
20_F24_R0.079320.851
78_V97_S0.078950.847
140_V151_L0.078640.844
101_L138_A0.078610.844
30_I153_L0.078250.840
22_I26_R0.078190.839
28_P57_I0.078070.838
92_F95_I0.078010.837
93_L150_V0.077890.836
22_I58_K0.077860.836
43_E49_P0.07780.835
10_L15_V0.077650.833
101_L156_R0.077490.832
29_R36_Y0.077440.831
8_I14_L0.077430.831
77_Y126_I0.077340.830
67_E126_I0.077310.830
25_K34_R0.077240.829
31_Y152_Y0.076860.825
80_L130_P0.07680.824
140_V144_Y0.076770.824
43_E47_P0.076750.824
9_N16_L0.076390.820
27_F47_P0.076360.819
100_V142_F0.076220.818
121_L124_L0.076170.817
137_W153_L0.076080.816
65_D86_L0.075930.815
51_R100_V0.075880.814
2_F126_I0.075840.814
27_F32_Q0.075560.811
121_L151_L0.075440.810
17_L154_L0.075410.809
149_Y153_L0.075380.809
64_S145_I0.075280.808
15_V156_R0.07510.806
23_L74_L0.074790.803
129_V135_R0.074670.801
25_K68_I0.074550.800
86_L154_L0.074450.799
42_P70_R0.074390.798
76_A123_R0.074070.795
43_E99_P0.073950.794
63_I71_H0.073880.793
95_I152_Y0.07380.792
31_Y34_R0.073780.792
19_L132_G0.073650.790
82_F110_D0.073580.790
64_S153_L0.073540.789
123_R149_Y0.073420.788
61_F95_I0.073410.788
82_F90_F0.073380.787
110_D127_S0.073130.785
18_L57_I0.073120.785
120_G124_L0.073020.784
16_L155_W0.072790.781
78_V82_F0.072760.781
100_V104_I0.072720.780
12_I96_L0.072690.780
6_L141_V0.072670.780
24_R97_S0.072330.776
11_I155_W0.072120.774
89_I95_I0.072030.773
19_L51_R0.071760.770
2_F16_L0.071220.764
100_V138_A0.071060.763
98_L131_K0.070920.761
125_T153_L0.070860.760
20_F31_Y0.070770.759
105_N128_N0.070760.759
119_S151_L0.07060.758
13_F20_F0.070580.757
104_I145_I0.070530.757
5_S102_L0.07040.755
23_L27_F0.070390.755
88_K156_R0.070270.754
83_L102_L0.070240.754
46_P78_V0.070210.753
23_L101_L0.07020.753
59_P62_K0.070090.752
37_L142_F0.070070.752
32_Q35_S0.070060.752
33_P122_D0.069640.747
5_S54_F0.069590.747
51_R98_L0.069470.745
65_D84_R0.069410.745
89_I149_Y0.069410.745
3_L124_L0.06940.745
43_E48_L0.069260.743
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1vffA0.44596.70.948
2ww9B0.49045.60.949
3mk7C0.49044.40.952
2llmA0.16563.60.954
1pfiA0.16562.70.956
3e4gA0.67522.50.957
2k9yA0.1722.50.957
1iijA0.1722.20.958
4il3A0.96182.10.959
2ls2A0.159220.959
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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