GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF4244 - Protein of unknown function (DUF4244)
Pfam: PF14029 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 56
Sequences: 707
Seq/Len: 12.62
HH_delta: 0.859 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
15_M27_A0.425551.910
15_M23_G0.421121.890
18_A27_A0.38411.724
45_S52_E0.36971.659
6_R9_L0.336081.508
35_Y39_T0.327811.471
9_L13_A0.319811.435
41_D48_T0.317711.426
17_T30_F0.314751.413
45_S49_G0.310381.393
16_S23_G0.295141.325
7_R10_R0.281291.262
18_A22_V0.274391.231
8_L11_D0.271961.220
16_S27_A0.259411.164
35_Y38_V0.253611.138
21_A47_L0.252831.135
15_M38_V0.252411.133
45_S48_T0.244441.097
15_M18_A0.232731.044
23_G37_V0.230131.033
47_L51_I0.228461.025
10_R36_K0.221620.995
8_L13_A0.219770.986
23_G27_A0.21860.981
6_R10_R0.216960.974
33_V51_I0.21550.967
49_G52_E0.214050.961
7_R49_G0.21090.946
9_L45_S0.209940.942
31_A43_V0.207820.933
23_G43_V0.204460.918
34_L37_V0.20250.909
40_S51_I0.201160.903
17_T21_A0.200860.901
7_R45_S0.199480.895
36_K39_T0.195780.879
18_A28_A0.193590.869
13_A31_A0.189970.853
6_R48_T0.186910.839
44_R52_E0.186740.838
15_M34_L0.186340.836
48_T52_E0.186280.836
7_R34_L0.182950.821
44_R51_I0.179850.807
28_A33_V0.179050.804
22_V32_G0.177710.798
41_D44_R0.176920.794
11_D49_G0.176630.793
6_R39_T0.17420.782
48_T51_I0.169650.761
10_R41_D0.169340.760
41_D45_S0.168260.755
7_R11_D0.165840.744
42_E51_I0.165050.741
12_D37_V0.163680.735
40_S44_R0.162480.729
22_V31_A0.162150.728
30_F47_L0.161070.723
16_S19_E0.159590.716
29_A33_V0.158590.712
35_Y44_R0.158190.710
8_L52_E0.158140.710
23_G34_L0.156170.701
8_L18_A0.155140.696
36_K44_R0.153040.687
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3eu8A0.91075.10.859
2v75A0.87550.86
3pjzA0.91073.10.873
4gl3A0.92862.90.874
1rm1C0.33932.80.874
3j21h0.32142.80.875
3nd0A0.96432.60.877
1elkA0.46432.30.881
2xi5A0.33932.20.881
3kn3A0.392920.883
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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