GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF4341 - Domain of unknown function (DUF4341)
Pfam: PF14241 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 62
Sequences: 772
Seq/Len: 12.45
HH_delta: 0.822 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
2_P5_A0.446262.367
29_I54_L0.403892.143
11_L14_L0.389092.064
27_A50_F0.363351.928
36_L48_L0.339391.800
35_G47_R0.338911.798
9_G13_G0.323841.718
32_I47_R0.317361.684
18_L22_L0.311451.652
20_L57_G0.29521.566
20_L30_S0.282091.496
7_I10_L0.25931.376
13_G50_F0.246041.305
19_L46_W0.22241.180
4_S57_G0.218461.159
51_L56_L0.217781.155
14_L41_K0.217771.155
5_A57_G0.21261.128
36_L44_R0.212521.127
33_L41_K0.212131.125
4_S61_A0.211551.122
38_S44_R0.208371.105
3_W61_A0.204661.086
15_A20_L0.199051.056
4_S10_L0.199041.056
18_L56_L0.191761.017
44_R48_L0.190741.012
20_L23_N0.190431.010
55_I59_F0.18560.985
29_I50_F0.184220.977
5_A58_G0.181890.965
5_A10_L0.178920.949
34_S58_G0.176480.936
31_G35_G0.175840.933
6_L9_G0.175760.932
19_L59_F0.175260.930
50_F58_G0.174160.924
26_I50_F0.173620.921
25_R36_L0.173470.920
13_G21_L0.172040.913
6_L15_A0.17110.908
19_L23_N0.167150.887
19_L58_G0.166680.884
49_A57_G0.165540.878
26_I31_G0.165310.877
6_L10_L0.16450.873
7_I34_S0.163850.869
8_G15_A0.163770.869
6_L16_A0.163320.866
10_L39_P0.163050.865
25_R58_G0.162570.862
39_P55_I0.157790.837
12_I54_L0.157420.835
13_G16_A0.157050.833
38_S56_L0.154660.820
24_G50_F0.154470.819
10_L14_L0.152870.811
7_I11_L0.152020.806
38_S41_K0.151540.804
10_L52_A0.150130.796
27_A37_L0.150120.796
8_G29_I0.150050.796
3_W7_I0.149970.796
41_K44_R0.147960.785
25_R53_G0.147330.782
45_D52_A0.146960.780
21_L56_L0.146910.779
17_S20_L0.146170.775
31_G39_P0.145410.771
18_L44_R0.145390.771
35_G43_D0.144060.764
38_S55_I0.143030.759
7_I40_N0.14290.758
21_L54_L0.142810.758
7_I59_F0.14220.754
33_L37_L0.139960.742
12_I27_A0.139490.740
15_A27_A0.139260.739
15_A33_L0.138950.737
42_P48_L0.137340.729
10_L18_L0.137250.728
2_P57_G0.135110.717
20_L26_I0.134870.715
12_I40_N0.133010.706
36_L42_P0.13290.705
38_S60_L0.132510.703
52_A57_G0.131130.696
38_S42_P0.129110.685
40_N43_D0.128380.681
26_I29_I0.127690.677
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3iyzA0.983917.40.822
2b6oA114.50.829
3llqA114.20.83
3cn5A112.30.833
3zojA18.40.845
1j4nA180.846
3d9sA17.70.848
2o9gA17.10.85
3gd8A15.60.856
2w2eA15.30.858
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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