GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF4351 - Domain of unknown function (DUF4351)
Pfam: PF14261 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 59
Sequences: 932
Seq/Len: 15.8
HH_delta: 0.792 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
14_R44_E0.873433.398
11_L43_A0.66872.602
18_R44_E0.592862.307
18_R48_D0.576712.244
34_L42_L0.522532.033
17_T28_Q0.456251.775
35_S38_Q0.393541.531
50_N54_D0.391651.524
14_R40_E0.382571.488
49_F55_L0.365481.422
24_P52_L0.353221.374
15_L46_I0.346711.349
14_R18_R0.343851.338
42_L45_A0.328251.277
5_Q9_A0.320291.246
43_A47_L0.319351.242
13_L31_I0.31771.236
3_G7_G0.316671.232
44_E48_D0.300241.168
42_L56_E0.288531.123
11_L47_L0.288521.123
8_E40_E0.280221.090
34_L49_F0.280161.090
16_L19_R0.275651.072
52_L56_E0.272261.059
29_E33_Q0.268811.046
38_Q41_A0.249280.970
4_R10_R0.245080.954
22_E25_P0.241480.940
28_Q32_Q0.236580.920
16_L23_L0.230710.898
15_L47_L0.22540.877
21_G34_L0.22510.876
9_A32_Q0.223460.869
49_F56_E0.222640.866
30_R56_E0.217630.847
13_L28_Q0.216440.842
43_A46_I0.214660.835
51_S56_E0.209180.814
25_P28_Q0.207880.809
41_A45_A0.207060.806
29_E32_Q0.206760.804
51_S54_D0.205160.798
12_L27_I0.20470.796
19_R23_L0.203620.792
24_P27_I0.203530.792
20_F52_L0.203520.792
34_L56_E0.202170.787
5_Q13_L0.198330.772
53_E56_E0.198040.771
30_R37_E0.196970.766
11_L15_L0.196860.766
40_E44_E0.196420.764
40_E43_A0.192530.749
31_I55_L0.189550.737
15_L19_R0.187410.729
21_G31_I0.187150.728
16_L55_L0.185870.723
35_S40_E0.185330.721
45_A49_F0.184680.719
14_R48_D0.184480.718
49_F54_D0.182260.709
3_G6_E0.181890.708
23_L26_E0.179290.698
8_E11_L0.179070.697
29_E50_N0.177790.692
19_R46_I0.177170.689
15_L34_L0.176680.687
9_A22_E0.175670.683
42_L49_F0.175640.683
11_L46_I0.172770.672
42_L55_L0.170090.662
26_E36_L0.167150.650
37_E41_A0.165650.644
27_I56_E0.165230.643
30_R52_L0.163980.638
28_Q33_Q0.16250.632
12_L20_F0.162260.631
17_T32_Q0.160830.626
20_F46_I0.157610.613
15_L54_D0.155530.605
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4anoA0.915318.80.792
1ywfA0.779715.50.799
2daeA0.898311.60.809
3qp1A0.66110.70.812
2wqdA110.50.813
2qsrA0.932290.817
2hwgA18.40.82
2fknA0.94928.30.82
1uwkA0.94928.20.821
1x87A0.94928.20.821
If you are interested in a protein containing this domain,
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