GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF4368 - Domain of unknown function (DUF4368)
Pfam: PF14287 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 71
Sequences: 374
Seq/Len: 5.27
HH_delta: 0.873 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
31_P35_N0.292072.134
44_H58_E0.287412.100
42_V58_E0.281072.054
22_K36_E0.268281.960
33_I62_N0.268181.960
26_I33_I0.237881.738
44_H56_K0.21751.589
61_Y67_I0.205231.500
26_I41_I0.196721.437
5_E11_E0.193331.413
8_Q12_D0.19181.401
37_L62_N0.181331.325
16_F22_K0.172351.259
60_Y66_K0.168981.235
39_D62_N0.164821.204
33_I39_D0.159911.168
4_S18_E0.15891.161
16_F35_N0.156961.147
9_K30_T0.150141.097
5_E24_T0.143251.047
7_E12_D0.140751.028
22_K57_I0.140491.027
20_I35_N0.137721.006
4_S14_D0.134680.984
34_L61_Y0.134150.980
19_L36_E0.13240.967
26_I29_L0.132230.966
5_E9_K0.130980.957
33_I67_I0.129770.948
8_Q17_I0.128440.938
11_E20_I0.126840.927
5_E43_V0.126820.927
10_S18_E0.126270.923
46_P55_Q0.126020.921
32_E35_N0.12470.911
55_Q61_Y0.12460.910
14_D41_I0.124190.907
13_V46_P0.124140.907
24_T36_E0.123780.904
27_T63_F0.122610.896
6_E38_I0.122480.895
12_D61_Y0.121910.891
21_R64_I0.121490.888
29_L34_L0.120660.882
28_E38_I0.120230.878
21_R24_T0.120070.877
4_S8_Q0.119440.873
5_E38_I0.118890.869
12_D42_V0.117870.861
17_I21_R0.117380.858
29_L37_L0.116570.852
33_I36_E0.116430.851
18_E27_T0.115080.841
20_I31_P0.114930.840
64_I67_I0.113440.829
29_L63_F0.113210.827
23_Y36_E0.113140.827
31_P41_I0.112820.824
29_L41_I0.112130.819
34_L55_Q0.111920.818
18_E34_L0.111310.813
29_L35_N0.11130.813
6_E59_I0.111140.812
34_L42_V0.108950.796
30_T44_H0.106790.780
15_K57_I0.105320.770
31_P44_H0.10410.761
59_I63_F0.103960.760
15_K66_K0.103890.759
15_K63_F0.103550.757
23_Y33_I0.10290.752
35_N65_G0.102640.750
16_F23_Y0.102030.746
6_E12_D0.101890.744
9_K20_I0.101790.744
24_T61_Y0.100090.731
8_Q14_D0.099960.730
12_D20_I0.099720.729
42_V60_Y0.099560.727
55_Q59_I0.09950.727
5_E14_D0.099360.726
20_I41_I0.096630.706
12_D35_N0.096190.703
24_T37_L0.09590.701
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3j21F0.70422.40.873
4h5gA0.43662.20.875
1v5pA0.43662.10.876
2rdgA0.943720.877
3hy3A0.887320.877
1et9A0.971820.877
2b3tB0.915520.878
4a6hA0.38031.90.878
3gjxA0.4931.90.879
2fh5A0.95771.90.879
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

Page generated in 0.0243 seconds.