GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
ABC_trans_N - ABC-transporter extracellular N-terminal
Pfam: PF14510 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 85
Sequences: 468
Seq/Len: 5.51
HH_delta: 0.894 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
3_R6_S0.308572.460
1_L6_S0.24951.989
77_P85_N0.217851.737
73_A77_P0.199031.587
39_W76_Q0.192741.537
43_F53_K0.190891.522
49_E53_K0.188391.502
48_E53_K0.184011.467
30_D56_K0.182461.455
49_E52_I0.175981.403
46_R52_I0.173881.386
36_L40_L0.173591.384
46_R49_E0.171251.365
67_Y71_A0.169641.352
29_P39_W0.169581.352
26_S38_R0.167511.335
25_S33_D0.164241.309
77_P81_N0.159651.273
29_P76_Q0.159391.271
35_D78_T0.157921.259
40_L57_A0.155921.243
45_R49_E0.154761.234
55_R84_L0.153991.228
43_F49_E0.152311.214
1_L79_V0.148471.184
58_G83_L0.146871.171
44_V53_K0.145961.164
43_F47_A0.144641.153
34_F68_G0.143861.147
27_L39_W0.143781.146
44_V48_E0.141131.125
42_N60_S0.140721.122
43_F48_E0.138971.108
34_F39_W0.138251.102
60_S64_L0.136781.090
24_D28_D0.13651.088
2_A6_S0.134021.068
35_D66_V0.133071.061
37_R74_Q0.131661.050
75_Y81_N0.131541.049
69_V74_Q0.128361.023
44_V47_A0.127481.016
1_L5_L0.127371.015
77_P82_V0.125431.000
35_D52_I0.125310.999
54_P62_K0.124680.994
33_D80_G0.123520.985
55_R80_G0.122810.979
43_F52_I0.122130.974
13_N59_V0.119250.951
35_D59_V0.117950.940
8_Q71_A0.117640.938
42_N78_T0.117510.937
24_D38_R0.116280.927
30_D65_T0.115670.922
60_S63_N0.11540.920
69_V77_P0.114060.909
28_D39_W0.113540.905
65_T78_T0.112510.897
65_T70_G0.112110.894
34_F38_R0.111230.887
25_S28_D0.110010.877
28_D62_K0.109970.877
28_D31_S0.10930.871
8_Q11_Q0.109290.871
69_V81_N0.108290.863
7_R32_D0.106530.849
34_F63_N0.105770.843
13_N22_T0.105370.840
40_L51_G0.104980.837
61_F67_Y0.10450.833
26_S83_L0.103890.828
11_Q49_E0.103780.827
44_V49_E0.103780.827
26_S40_L0.103150.822
58_G79_V0.102770.819
36_L81_N0.102720.819
1_L4_T0.102650.818
80_G83_L0.102440.817
14_P38_R0.102230.815
45_R48_E0.102070.814
5_L73_A0.102020.813
55_R66_V0.100560.802
40_L55_R0.10010.798
26_S63_N0.100080.798
23_S59_V0.099930.797
14_P21_T0.099820.796
4_T33_D0.099760.795
79_V84_L0.09960.794
3_R56_K0.099050.790
54_P78_T0.098740.787
38_R44_V0.098560.786
43_F51_G0.098270.783
45_R51_G0.098160.783
2_A27_L0.09810.782
37_R41_R0.09790.781
6_S35_D0.097440.777
48_E51_G0.09740.777
5_L82_V0.096940.773
56_K63_N0.095660.763
14_P57_A0.094810.756
6_S54_P0.09440.753
50_Q53_K0.094210.751
73_A81_N0.094080.750
55_R69_V0.093530.746
6_S22_T0.093150.743
3_R35_D0.093130.742
46_R75_Y0.093090.742
71_A82_V0.093040.742
1_L63_N0.092440.737
46_R50_Q0.091920.733
33_D41_R0.091880.733
55_R58_G0.091470.729
24_D42_N0.091120.726
4_T11_Q0.09080.724
1_L8_Q0.090630.723
4_T10_S0.090520.722
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1t94A0.84.50.894
2xm5A0.67063.70.899
3sscA0.57653.70.899
3mfiA0.78823.70.899
2xsaA0.89413.40.9
2eqaA0.65883.10.902
2akkA0.51762.70.904
1hruA0.57652.60.905
3d1nI0.62352.60.905
1zdyA0.62.50.906
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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